The following is a summary of the Arbutus Biopharma Corporation (ABUS) Q1 2024 Earnings Call Transcript:

Financial Performance:

• Arbutus ended Q1 2024 with cash, cash equivalents, and investments of around $138 million, increasing from $132 million as of December 2023.

• They received $21.8 million in net proceeds from the issuance of common shares, offset by $19.3 million of cash used in operations.

• An additional $22.4 million was generated in April 2024 from their ATM program.

• The estimated net cash burn for 2024 is expected to be within the range of $63 million to $67 million.

Business Progress:

• Arbutus initiated the AB-101 Phase 1a/1b clinical trial and the Phase 2a clinical trial with imdusiran and durvalumab aimed at HBV cure.

• The company's strategy emphasizes combination therapy, and it's advancing the proprietary oral molecule checkpoint inhibitor AB-101.

• End-of-treatment data from multiple trials, including AB-729-201 and 202, are expected throughout 2024.

• Arbutus is involved in ongoing LNP patent infringement lawsuits against Moderna and Pfizer/BioNTech, progressing towards an April 2025 trial date.

• The company announced the retirement of Co-Founder and Chief Scientific Officer, Dr. Mike Sofia.

• Arbutus has been conducting a three-part study on AB-101, and plans to share preliminary end treatment data in the second half of the year.

More details: Arbutus Biopharma IR

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