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SeqLL Announces Formation of Scientific Advisory Board

SeqLL Announces Formation of Scientific Advisory Board

工商局局長宣佈成立科學顧問委員會
GlobeNewswire ·  2022/03/21 16:26

BILLERICA, Mass., March 21, 2022 (GLOBE NEWSWIRE) -- SeqLL Inc. ("SeqLL" or the "Company") (NASDAQ: SQL; SQLLW), a technology company providing life sciences instrumentation and research services for collaborative partnerships, today announced the formation of a Scientific Advisory Board ("SAB") comprised of distinguished and world-renowned leaders of the scientific community. The SAB will discuss with management potential new development opportunities that leverage the Company's unique True Single Molecule Sequencing (tSMS®) technology across the "omics" fields, as well as advise management with their existing collaborative, scientific, & development partnerships. Each leader has previously utilized the tSMS platform and will leverage their expertise to provide valuable insight to our company.

馬薩諸塞州比勒裏卡,2022年3月21日(Global Newswire)--為合作伙伴關係提供生命科學儀器和研究服務的技術公司SeqLL Inc.(以下簡稱SeqLL或本公司)(納斯達克代碼:SQL;SQLLW)今天宣佈成立一個科學顧問委員會,該委員會由科學界傑出的世界知名領袖組成。SAB將與管理層討論潛在的新發展機會,利用公司在“組學”領域的獨特真單分子測序(TSMS®)技術,並與現有的合作、科學和開發夥伴關係向管理層提供建議。每一位領導者之前都使用過TSMS平臺,並將利用他們的專業知識為我們的公司提供寶貴的見解。

"We are privileged to be working with this distinguished and talented group of scientific advisors as we expand the reach of our tSMS technology," said Daniel Jones, CEO, President, and Co-Founder of SeqLL. "These advisors bring valuable scientific insight and industry contacts to our work and will assist us in becoming a world-class leader in creating novel assets with our true single molecule sequencing technology."

SeqLL首席執行官、總裁兼聯合創始人丹尼爾·瓊斯表示:“在我們擴大TSMS技術覆蓋範圍的過程中,我們很榮幸能與這羣傑出而有才華的科學顧問合作。這些顧問為我們的工作帶來了寶貴的科學見解和行業聯繫,並將幫助我們成為用我們真正的單分子測序技術創造新資產的世界級領先者。“

Leaders of the SeqLL Scientific Advisory Board include:

SeqLL科學顧問委員會的領導人包括:

Claes Wahlestedt, M.D., Ph.D., Chairman of the SAB. Director of the Center for Therapeutic Innovation, Leonard M. Miller School of Medicine, University of Miami. Dr. Wahlestedt has a long-standing academic as well as big pharma career in drug discovery, genomics and epigenetics, and has pioneered various translational efforts in these fields. From 2005 to 2011, Dr. Wahlestedt was a professor and a director at The Scripps Research Institute. Prior to that he founded and ran the genomics and bioinformatics center at the Karolinska Institute (a joint venture with Pharmacia/Pfizer). Among companies he has co-founded are CuRNA (now part of Opko Health/Camp4), based on his patent for targeting regulatory noncoding RNAs to up-regulate therapeutic proteins, and Epigenetix Inc., focusing on small molecule drugs for a variety of drug targets in cancer and neuroscience. He is the author of over 300 papers in scientific journals, with over 45,000 citations. Dr. Wahlestedt is an expert in genomic medicine pertaining to a number of innovative therapeutic modalities and diagnostic approaches.

Claes Wahlestedt,醫學博士,SAB主席。邁阿密大學倫納德·M·米勒醫學院治療創新中心的董事説。Wahlestedt博士在藥物發現、基因組學和表觀遺傳學方面有着長期的學術和大型製藥行業的職業生涯,並在這些領域開創了各種翻譯工作。從2005年到2011年,瓦赫斯泰特博士是斯克裏普斯研究所的教授和董事研究員。在此之前,他在卡羅林斯卡研究所(與Pharmacia/Pfizer的合資企業)創建並運營了基因組學和生物信息學中心。他聯合創立的公司包括CuRNA(現在是Opko Health/Camp4的一部分),該公司基於他的專利,以靶向調節性非編碼RNA來上調治療性蛋白質,以及Eigenetix Inc.,專注於針對癌症和神經科學中各種藥物靶點的小分子藥物。他在科學期刊上發表了300多篇論文,被引用超過45000篇。Wahlestedt博士是基因組醫學方面的專家,與許多創新的治療方式和診斷方法有關。

L. Frank Kolakowski, Ph.D., Senior Scientist, Tetracore, Inc. Dr. Kolakowski has a distinguished 30-year scientific research career that includes positions on the faculty of the University of Texas Health Science Center, as an instructor at Harvard Medical School, and as consultant for several U.S. government agencies. As an entrepreneur, Dr. Kolakowski founded and served as CEO of ReceptorBase from 2000-2004, prior to being hired by the prestigious consulting firm Booz Allen Hamilton to initiate and manage their life sciences practice. He received his Doctorate in Chemistry from the University of Pennsylvania and his B.S. in Biology and Chemistry from Towson State University. Tetracore and Dr. Kolakowski are long term partners of SeqLL.

L.Frank Kolakowski,博士Kolakowski博士擁有30年卓越的科學研究生涯,曾在德克薩斯大學健康科學中心擔任教員、哈佛醫學院講師和多個美國政府機構的顧問。作為一名企業家,Kolakowski博士在2000-2004年間創立並擔任ReceptorBase的首席執行官,之後受僱於著名的諮詢公司Booz Allen Hamilton,啟動和管理他們的生命科學業務。他在賓夕法尼亞大學獲得化學博士學位,在陶森州立大學獲得生物和化學學士學位。Tetracore和Kolakowski博士是SeqLL的長期合作伙伴。

Efrat Shema, Ph.D., Principal Investigator and Assistant Professor at the Weizmann Institute of Science. Recipient of the prestigious Fulbright Scholar, Dr. Shema conducted post-doctoral work under Dr. Bradley Bernstein at Massachusetts General Hospital, Harvard Medical School, and the Broad Institute of MIT and Harvard. During her Ph.D. studies at the Weizmann Institute, Dr. Shema has received multiple prestigious awards, including the Adams Fellowship from the Israel Academy of Sciences and Humanities, the Otto Schwartz Prize for Excellence, and the UNESCO-L'OREAL national award for young women in life sciences. Dr. Shema completed her M.Sc. and Ph.D in molecular cell biology at the Weizmann Institute and earned her B.Sc. in life sciences at the Hebrew University in Jerusalem in 2005.   Dr. Shema's research has focused on using SeqLL's tSMS platform to decode the cancer epigenome since 2014.

Efrat Shema,博士魏茨曼科學研究所首席研究員兼助理教授。謝馬博士獲得了著名的富布賴特學者獎,在布拉德利·伯恩斯坦博士的指導下,在馬薩諸塞州總醫院、哈佛醫學院以及麻省理工學院和哈佛大學的博士後研究所進行了博士後工作。在魏茨曼研究所攻讀博士期間,謝瑪博士獲得了多個著名獎項,包括以色列科學院和人文學院頒發的亞當斯獎學金、奧託·施瓦茨優秀獎和聯合國教科文組織-歐萊雅生命科學領域年輕女性獎。謝馬博士完成了她的理學碩士學位。在魏茨曼研究所獲得分子細胞生物學博士學位,並獲得理科學士學位。2005年在耶路撒冷希伯來大學攻讀生命科學專業。自2014年以來,舍馬博士的研究重點一直是使用SeqLL的TSMS平臺來解碼癌症表觀基因組。

Timothy McCaffrey, Ph.D., Professor of Medicine and Director, Division of Genomic Medicine, George Washington University. Dr. McCaffrey has had a distinguished career in research focused in three major areas: cardiovascular disease, genomics and stem cells. In 2001, he received a prestigious MERIT award from NIH for his work on vascular aging. Dr. McCaffrey is a close collaborator of ours and has used the tSMS platform to identify several panels of RNA transcripts that are highly predictive biomarkers in the fields of cardiovascular disease, infection and inflammation. He co-founded True Bearing Diagnostics to commercialize diagnostics based on those discoveries. He received post-doctoral training at Cornell University Medical College in New York City, his Masters and Doctorate from Purdue University and his B.A. from St. Mary's University.

蒂莫西·麥卡弗裏博士,喬治華盛頓大學基因組醫學系醫學和董事教授。麥卡弗裏博士在心血管疾病、基因組學和幹細胞這三個主要領域的研究領域取得了卓越的成就。2001年,他因在血管老化方面的工作而獲得美國國立衞生研究院頒發的享有盛譽的功勛獎。McCaffrey博士是我們的密切合作夥伴,他利用TSMS平臺識別了幾組RNA轉錄本,這些轉錄本在心血管疾病、感染和炎症領域具有高度預測性的生物標誌物。他與人共同創立了True軸承診斷公司,將基於這些發現的診斷技術商業化。他在紐約市康奈爾大學醫學院接受博士後培訓,在普渡大學獲得碩士和博士學位,在聖瑪麗大學獲得學士學位。

About True Single Molecule Sequencing (tSMS) Technology
SeqLL's collaborators are thoroughly committed to using only our tSMS platform in their scientific research due to its unique RNA and DNA sequencing and related services. Our true single molecule sequencing platform is NGS technology offers maximum flexibility and avoids many of the challenges common for standard NGS approaches. It that enables direct sequencing of millions of individual molecules not requiring PCR amplification at any stage of the process and a simple, economical sample prep protocols. Therefore, it captures a precise sample composition, without bias and loss of diversity and rare species. Our tSMS platform is ideally suited for RNA biomarker discovery and diagnostic assay developments, including challenging applications for the standard NGS platform, such as low quantity, difficult or degraded samples of cell-free DNA, FFPE-isolated nucleic acids, ancient DNA and forensic samples.

關於真單分子測序(TSMS)技術
SeqLL的合作者完全致力於在他們的科學研究中只使用我們的TSMS平臺,因為它具有獨特的RNA和DNA測序及相關服務。我們真正的單分子測序平臺是NGS技術,提供了最大的靈活性,避免了標準NGS方法常見的許多挑戰。它使數百萬個單獨的分子能夠直接測序,而不需要在過程的任何階段進行PCR擴增,以及簡單、經濟的樣品製備方案。因此,它捕獲了準確的樣品組成,沒有偏見,沒有多樣性和稀有物種的損失。我們的TSMS平臺非常適合於RNA生物標記物的發現和診斷分析開發,包括標準NGS平臺的挑戰性應用,例如低數量、困難或降解的無細胞DNA樣本、FFPE分離的核酸、古代DNA和法醫樣本。

About SeqLL, Inc.
SeqLL Inc. ("SeqLL") is a technology company providing life sciences instrumentation and research services in collaborative partnerships aimed at the development of novel scientific assets and intellectual property across multiple "omics" fields. The Company leverages its expertise with its True Single Molecule Sequencing ("tSMS®") platform to empower scientists and researchers with improved genetic tools to better understand the molecular mechanisms of disease that is essential to the continued development of new breakthroughs in genomic medicine, and that hopefully address the critical concerns involved with today's precision medicine. In sum, our experienced team works with our collaborators to develop innovative solutions tailored to the needs of each specific project.

SeqLL公司簡介
SeqLL Inc.(“SeqLL”)是一家以合作伙伴關係提供生命科學儀器和研究服務的技術公司,旨在跨多個“組學”領域開發新的科學資產和知識產權。該公司利用其真正的單分子測序(“TSMS®”)平臺的專業知識,為科學家和研究人員提供改進的基因工具,使他們能夠更好地瞭解疾病的分子機制,這對繼續發展基因組醫學的新突破至關重要,並有望解決與當今精確醫學相關的關鍵問題。總而言之,我們經驗豐富的團隊與我們的合作者一起開發針對每個特定項目的需求而量身定做的創新解決方案。

Forward Looking Statements
This press release contains certain forward-looking statements, including those related to the applicability and viability of the Company's technology to quantifying RNA molecules from blood and other statements that are predictive in nature. Forward-looking statements are based on the Company's current expectations and assumptions. The Private Securities Litigation Reform Act of 1995 provides a safe-harbor for forward-looking statements. These statements may be identified by the use of forward-looking expressions, including, but not limited to, "expect," "anticipate," "intend," "plan," "believe," "estimate," "potential," "predict," "project," "should," "would" and similar expressions and the negatives of those terms. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this presentation. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in the Company's filings with the Securities and Exchange Commission, including its registration statement on Form S-1, as amended, under the caption "Risk Factors."

前瞻性陳述
本新聞稿包含某些前瞻性陳述,包括與該公司量化血液中RNA分子的技術的適用性和可行性有關的陳述,以及其他具有預測性的陳述。前瞻性陳述是基於公司目前的預期和假設。1995年的《私人證券訴訟改革法》為前瞻性陳述提供了避風港。這些表述可以通過使用前瞻性表述來識別,包括但不限於“預期”、“預期”、“打算”、“計劃”、“相信”、“估計”、“潛在”、“預測”、“項目”、“應該”、“將”以及類似的表述和這些術語的否定。告誡潛在投資者不要過度依賴此類前瞻性陳述,這些陳述僅在本報告發表之日發表。公司不承擔公開更新任何前瞻性陳述的義務,無論是由於新信息、未來事件還是其他原因。可能導致實際結果與前瞻性陳述大不相同的重要因素在該公司提交給證券交易委員會的文件中陳述,包括其在“風險因素”標題下的S-1表格註冊陳述。

Contacts:

聯繫人:

Ashley R. Robinson
LifeSci Advisors, LLC
Tel: +1 (617) 430-7577
Email: arr@lifesciadvisors.com

阿什利·R·羅賓遜
生活科學顧問有限責任公司
電話:+1(617)430-7577
電子郵件:arr@lifescivisors.com


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