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Zentek Engages Vimta Labs for Clinical Research

Zentek Engages Vimta Labs for Clinical Research

Zentek聘請Vimta實驗室進行臨牀研究
Accesswire ·  2022/03/10 08:06

GUELPH, ON / ACCESSWIRE / March 10, 2022 / Zentek Ltd. ("ZEN" or the "Company") (TSX-V:ZEN and OTC PINK:ZENYF), a Canadian IP (Intellectual Property) development and commercialization company focused on next-gen healthcare solutions, today announces that it has retained Vimta Labs Limited ("Vimta"), a leading clinical research organization in India, to begin studies of ZEN's ZenGUARD™ active ingredient as a potential treatment of infectious skin disease.

Guelph,on/ACCESSWIRE/2022年3月10日/Zentek Ltd. ("禪宗“或”公司)(多倫多證券交易所股票代碼:ZEN和OTC PINK:ZENYF),一家專注於下一代醫療解決方案的加拿大知識產權(知識產權)開發和商業化公司,今天宣佈,它已經聘請了印度領先的臨牀研究機構Vimta Labs Limited(簡稱Vimta),開始對Zen的Zen進行研究警衞™活性成分作為治療感染性皮膚病的潛在藥物。

Vimta will be performing pre-clinical research on ZEN's novel graphene oxide-silver active ingredient including collecting the ­in vitro and in vivo data that is required for the submission of an Investigational New Drug to the United States Food and Drug Administration (FDA) which is a requirement for the administration of a new drug in humans.

Vimta將對Zen的新型氧化石墨烯-銀活性成分進行臨牀前研究,包括收集體外和體內向美國食品和藥物管理局(FDA)提交研究用新藥所需的數據,這是在人體內使用新藥的要求。

The pre-clinical program includes the following research:

臨牀前計劃包括以下研究:

  1. The permeation of the graphene oxide-silver active ingredient in three different formulations to select a formulation that will be used for the remaining studies;
  2. Analytical and bioanalytical studies to calibrate the detection of the active ingredient in biological samples;
  3. Acute studies of high dosages of the active ingredient for dermal application;
  4. Genetic toxicity studies; and
  5. Safety pharmacology studies and general toxicity studies.
  1. 石墨烯氧化物-銀活性成分在三種不同配方中的滲透,以選擇將用於剩餘研究的配方;
  2. 進行分析和生物分析研究,以校準生物樣品中活性成分的檢測;
  3. 皮膚應用的高劑量活性成分的急性研究;
  4. 遺傳毒性研究;以及
  5. 安全性藥理研究和一般毒性研究。

The pre-clinical work with Vimta will begin immediately and is scheduled to be completed by Q4 2022.

Vimta的臨牀前工作將立即開始,計劃於2022年第四季度完成。

The Company decided to move forward with this work following cytotoxicity studies with Nucro-Technics and positive anecdotal results of various human skin infections including acne, warts and toenail fungal infections. There were no adverse effects recorded during these anecdotal trials.

該公司在利用Nucro-Technics進行了細胞毒性研究,並在包括粉刺、疣和趾甲真菌感染在內的各種人類皮膚感染的軼事結果呈陽性後,決定推進這項工作。在這些軼事試驗中,沒有記錄到不良反應。

These human anecdotal cases form part of ZEN's patent application filed December 21, 2021, under the Patent Cooperation Treaty entitled "Graphene-Silver Nanocomposites and Uses For Same As a Broad-Spectrum Antimicrobial" which is scheduled to be published on June 22, 2022.

這些人類軼事案例是Zen根據專利合作條約提交的2021年12月21日提交的專利申請的一部分,該條約題為《石墨烯-銀納米複合材料及其作為廣譜抗菌劑的用途》,該條約計劃於2022年6月22日公佈。

Dr. Kenneth Reed, Dermatologist commented: "Although anecdotal observations are encouraging, the rigorous scientific analysis performed by Vimta will ensure the safety, formulation, and fortify the basic required data needed for FDA review, prior to the potential launch of a new therapeutic agent. The broad-spectrum antimicrobial effects of ZenGUARD™ make it particularly attractive as a topical formulation for the treatment of cutaneous disease with an infectious etiology."

皮膚科醫生Kenneth Reed評論説:“雖然軼事觀察令人鼓舞,但Vimta進行的嚴格科學分析將確保安全性、配方和加強FDA審查所需的基本數據,在可能推出新的治療劑之前。Zen的廣譜抗菌作用警衞™使其作為治療感染性皮膚病的外用製劑特別有吸引力。“

"This is another excellent example of the application opportunities for our broad-spectrum, patent-pending ZenGUARD™ technology," said Dr. Francis Dubé, Executive Chair at Zentek Ltd. "Consistent with our mission to develop innovative nanotechnologies with our partners, Vimta's commitment to high-quality standards and building sustainable relationships will help Zentek to continue creating solutions that improve people's lives."

這是我們正在申請專利的廣譜禪宗應用機會的又一個極好的例子。警衞™公司執行主席Francis Dubé博士説,“與我們與合作伙伴共同開發創新納米技術的使命一致,Vimta對高質量標準和建立可持續關係的承諾將幫助Zentek繼續創造改善人們生活的解決方案。”

About Zentek Ltd.

關於Zentek Ltd.

Zentek is an IP development and commercialization company focused on next-gen healthcare solutions in the areas of prevention, detection and treatment. Zentek is currently focused on commercializing ZenGUARD™, a patent-pending coating shown to have 99% antimicrobial activity, including against COVID-19, and the potential to use similar compounds as products against infectious diseases. The Company also has an exclusive agreement to be the global exclusive commercializing partner for a newly developed aptamer-based rapid pathogen detection technology.

Zentek是一家知識產權開發和商業化公司,專注於預防、檢測和治療領域的下一代醫療解決方案。Zentek目前專注於將禪宗商業化警衞™,一種正在申請專利的塗料,被證明具有99%的抗菌活性,包括對新冠肺炎的抗菌活性,並有可能將類似化合物用作治療傳染病的產品。該公司還達成了一項獨家協議,將成為一種新開發的基於適體的快速病原體檢測技術的全球獨家商業化合作夥伴。

For further information:

有關更多信息,請訪問:

Matt Blazei
Tel: (212) 655-0924
Email: mattb@coreir.com

馬特·布拉澤
電話:(212)655-0924
電子郵件:mattb@coreir.com

To find out more about Zentek Ltd., please visit our website at . A copy of this news release and all material documents in respect of the Company may be obtained on ZEN's SEDAR profile at

欲瞭解更多有關Zentek Ltd.的信息,請訪問我們的網站:。本新聞稿和與公司有關的所有重要文件的副本可在Zen的SEDAR簡介中獲得,網址為

Forward-Looking Statements

前瞻性陳述

This news release contains forward-looking statements. Since forward-looking statements address future events and conditions, by their very nature they involve inherent risks and uncertainties. Although Zentek believes that the assumptions and factors used in preparing the forward-looking information in this news release are reasonable, undue reliance should not be placed on such information, which only applies as of the date of this news release, and no assurance can be given that such events will occur in the disclosed time frames or at all. Zentek disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, other than as required by law.

本新聞稿包含前瞻性陳述。由於前瞻性陳述涉及未來的事件和情況,它們本身就具有內在的風險和不確定性。儘管Zentek認為,在準備本新聞稿中的前瞻性信息時使用的假設和因素是合理的,但不應過度依賴這些信息,因為這些信息僅適用於本新聞稿發佈之日,並且不能保證此類事件將在披露的時間框架內發生或根本不會發生。除法律要求外,Zentek沒有任何更新或修改任何前瞻性信息的意圖或義務,無論是由於新信息、未來事件還是其他原因。

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

多倫多證券交易所創業板交易所及其監管服務提供商(該術語在多倫多證券交易所的政策中定義)均不對本新聞稿的充分性或準確性承擔責任。

SOURCE: Zentek Ltd.

資料來源:Zentek Ltd.


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