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Bausch Health, Canada Inc. Announces Additional Public Drug Plan Listings for PrUCERIS (Budesonide) Aerosol Foam to Treat Mild to Moderate Distal Ulcerative Colitis in Adults

Bausch Health, Canada Inc. Announces Additional Public Drug Plan Listings for PrUCERIS (Budesonide) Aerosol Foam to Treat Mild to Moderate Distal Ulcerative Colitis in Adults

Bausch Health, Canada Inc.宣佈了用於治療成人輕度至中度遠端潰瘍性結腸炎的pruceris(布地奈德)氣溶膠泡沫的更多公共藥物計劃清單
Bausch Health ·  05/23 00:00

LAVAL, QC, May 23, 2024 - Bausch Health, Canada Inc., part of Bausch Health Companies Inc. (NYSE: BHC) (TSX: BHC), today announced additional Canadian public drug plan listings for PrUCERIS (budesonide) aerosol foam to treat mild to moderate distal ulcerative colitis in adults.1

加拿大鮑氏保健公司子公司鮑氏健康公司(紐交所:bausch health)(tsx:BHC),於2024年5月23日在魁北克省拉瓦爾宣佈,對PrUCERIS(布地奈德)氣霧泡沫在加拿大公共藥品計劃方面進行了增補,用於治療成年人輕度至中度遠端潰瘍性結腸炎。BHC此外,UCERIS最近成爲阿爾伯塔、愛德華王子島和紐芬蘭與拉布拉多省的公共藥品計劃以及非保險健康福利(NIHB)和加拿大退伍軍人事務部的土著人聯邦藥品計劃的受益者使用的藥品。1

UCERIS has most recently become available for patients through the public drug plans of Alberta, Prince Edward Island and Newfoundland and Labrador, as well as to beneficiaries of the federal drug plans for Indigenous people through the Non-Insured Health Benefit (NIHB) and Veterans Affairs Canada.

今年早些時候,UCERIS已經通過安大略、魁北克、薩斯喀徹溫、新不倫瑞克和新斯科舍省的公共藥品計劃爲患者提供服務。

Earlier this year, UCERIS was made available for patients through the public drug plans of Ontario, Quebec, Saskatchewan, New Brunswick and Nova Scotia.

"我們非常高興這些進一步的UCERIS公共藥品計劃清單意味着更多患有遠端潰瘍性結腸炎的加拿大患者現在可以接受這種新的治療方法,"鮑氏健康公司歐洲和加拿大高級副總裁Cees Heiman說。"鼓勵的是,在我們與泛加拿大製藥聯盟談判達成初步協議後,這些公共藥品計劃很快就完成了他們的清單。"

"We are very pleased that these further public drug plan listings for UCERIS mean more Canadians with distal ulcerative colitis now have access to this new therapy," said Cees Heiman, Senior Vice-President, Europe and Canada, Bausch Health. "It is encouraging that these public drug plans have moved quickly to finalize their listings after our agreement in principle following negotiations with the pan-Canadian Pharmaceutical Alliance."

UCERIS是該公司不斷壯大的腸道系列產品中的一員,自2023年9月以來已經可以通過處方在加拿大使用,也覆蓋了加拿大大多數私人保險藥品計劃。

UCERIS, part of the Company's growing gastrointestinal franchise, has been available in Canada by prescription since September 2023 and is also covered by the majority of private insurance drug plans in Canada.

UCERIS是加拿大唯一適用於治療成年患者活躍的輕度至中度遠端潰瘍性結腸炎,達到肛緣40厘米的糖皮質激素直腸泡沫,請參閱Bausch Health,加拿大公司,UCERIS直腸泡沫產品說明書

UCERIS is the only glucocorticosteroid rectal foam available in Canada indicated for the induction of remission in adult patients with active mild to moderate distal ulcerative colitis extending up to 40 cm from the anal verge.1 In a study comparing budesonide foam and budesonide enema in patients with active distal ulcerative colitis, most patients (84%) preferred the foam formulation because of its better tolerability and easier application.2

在比較活躍的遠單潰瘍性結腸炎患者中,使用布地奈德泡沫和布地奈德灌腸作爲醫療手段的研究表明,大多數患者(84%)更喜歡泡沫製劑,因爲它更容易忍受和使用。2

Ulcerative colitis is a chronic disease affecting the large intestine, or colon. The condition causes inflammation and ulceration (sores) along the lining of the colon, which can lead to abdominal pain, cramps, bleeding and diarrhea.3 In ulcerative colitis, the inflammation starts at the rectum and continues through the colon. Symptoms include diarrhea with blood and mucus, pain on the left-hand side of the abdomen, urgency and tenesmus (the feeling of needing to pass stools even if the bowel is empty).3

潰瘍性結腸炎是一種影響腸道或結腸的慢性疾病。該病症會導致盲腸壁內部的慢性炎症和潰瘍形成。症狀包括:下腹痛、腹痛、腹瀉和便血、大便等。3

In the two clinical studies on which the approval of UCERIS rectal aerosol foam was based, a significantly higher proportion of patients in the UCERIS group than in the placebo group were in remission at Week 6 (38.3% and 44.0% vs. 25.8% and 22.4% respectively, pooled p<0.0001) and had a rectal bleeding sub-score of 0 at Week 6 (46.6% and 50.0% vs. 28.0% and 28.6% respectively, pooled p<0.0001). There was also a higher proportion of patients in the UCERIS group than in the placebo group with an endoscopy sub-score of 0 or 1 at Week 6 (55.6% and 56.0% vs. 43.2% and 36.7% respectively.1

在UCERIS直腸泡沫的兩項臨床研究中,UCERIS組和安慰劑組的患者在第6周的緩解比例明顯高於各自的安慰劑組(分別爲38.3%和44.0%與25.8%和22.4%,混合p1

About Bausch Health
Bausch Health Companies Inc. (NYSE/TSX: BHC) is a global diversified pharmaceutical company enriching lives through our relentless drive to deliver better health outcomes. We develop, manufacture and market a range of products, primarily in gastroenterology, hepatology, neurology, dermatology, medical aesthetic devices, international pharmaceuticals, and eye health, through our controlling interest in Bausch + Lomb. Our ambition is to be a globally integrated healthcare company, trusted and valued by patients, healthcare professionals, employees and investors. For more information, visit www.bauschhealth.com and connect with us on Twitter and LinkedIn.

關於Bausch Health
Bausch Health公司(紐交所/TSX:BHC)是一家全球性多元化製藥公司,通過我們對實現更好健康結果的不懈追求,爲人們的生命增添光彩。我們開發、製造和銷售一系列產品,主要用於胃腸病、肝病、神經病學、皮膚病學、醫學美容器械、國際藥品和眼睛健康,通過對鮑氏朗寶的控股利益。我們的抱負是成爲一個全球一體化的醫療保健公司,受到患者、醫療保健專業人員、員工和投資者的信任和重視。欲了解更多信息,請訪問。www.bauschhealth.com並通過推特和頁面。LinkedIn.

The Bausch Health Canadian prescription treatment portfolio is focused on dermatology, gastrointestinal and cardio-metabolic conditions. Bausch Health also has two manufacturing facilities for prescription pharmaceuticals in Canada: in Laval, Quebec, and Steinbach, Manitoba. More information can be found at the Company's website at www.bauschhealth.ca.

鮑氏健康公司在加拿大的處方品治療業務組合側重於皮膚科、胃腸和心血管傳統領域。鮑氏健康公司在魁北克省拉瓦爾市和馬尼托巴省斯坦巴赫設有兩個處方藥品製造工廠。更多信息請登錄公司網站。www.bauschhealth.ca.

References
1 Bausch Health, Canada Inc., UCERIS rectal foam Product Monograph, https://bauschhealth.ca/wp- content/uploads/2022/06/Uceris-PM-E-2020-04-15.pdf.
2 Gross V, et al, Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis, Aliment Pharmacol Ther. 2006;23(2):303-312.
3 IBD Clinic, University of Alberta: http://www.ibdclinic.ca/what-is-ibd/ulcerative-colitis/.

參考
1鮑氏健康加拿大公司,UCERIS直腸泡沫產品說明書,請參閱https://bauschhealth.ca/wp- content/uploads/2022/06/Uceris-PM-E-2020-04-15.pdf。
2 Gross V, 等人,Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis,阿利門藥物治療。2006年23(2):303-312。Aliment Pharmacol Ther藥品
阿爾伯塔大學3號IBD診所:http://www.ibdclinic.ca/what-is-ibd/ulcerative-colitis/

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