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Theralase(R) Demonstrates 8 Year Shelf Life of Lead Drug Ruvidar(TM)

Theralase(R) Demonstrates 8 Year Shelf Life of Lead Drug Ruvidar(TM)

Theralase (R) 演示鉛藥物 Ruvidar (TM) 的保質期爲 8 年
Accesswire ·  2023/09/29 07:00

TORONTO, ON / ACCESSWIRE / September 29, 2023 / Theralase Technologies Inc. ("Theralase" or the "Company") (TSXV:TLT)(OTCQB:TLTFF) is a clinical stage pharmaceutical company that is dedicated to the research and development of light and radiation activated Photo Dynamic Compounds ("PDCs"), their associated drug formulations and the light systems that activate them. These PDCs are intended to safely and effectively destroy various cancers, bacteria and viruses, when light or radiation activated.

多倫多,2023年9月29日/ACCESSWIRETheralase Technologies Inc.(“Theralase“或”公司“)(TSXV:TLT)(OTCQB:TLTFF)是一家臨床階段的製藥公司,致力於光和輻射激活的光動力化合物的研究和開發。PDC“),它們的相關藥物配方和激活它們的光系統。這些PDC的目的是在光或輻射激活時安全有效地摧毀各種癌症、細菌和病毒。

Supported by current Good Manufacturing Practice ("cGMP") analysis conducted by an independent manufacturing and testing laboratory, Theralase announced that it has successfully demonstrated an 8 year, real-time, shelf life of its lead PDC, RuvidarTM.

由現行良好製造規範支持(“CGMP由一家獨立的製造和測試實驗室進行的分析,Theralase宣佈它已經成功地展示了其主要PDC Ruvidar的8年即時保質期TM

Dr. Arkady Mandel, MD, PhD, DSc, Chief Scientific Officer of Theralase stated, "Theralase's ability to demonstrate such an extended shelf life of its lead PDC, RuvidarTM is extremely encouraging, as it supports our ongoing clinical development plans. This independent analysis confirms the ability of RuvidarTM to be an extremely stable small molecule that has the ability to maintain its potency and purity over 8 years without significant degradation. This will allow our clinical partners to procure and store our PDC technology over many years without loss of clinical performance, minimizing the requirement to dispose of / replace unused drug over time."

Theralase的首席科學官Arkady Mandel博士,醫學博士,博士,DSC說:“Theralase有能力證明其主要的PDC Ruvidar的保質期如此之長TM這是非常令人鼓舞的,因為它支持我們正在進行的臨床開發計劃。這一獨立分析證實了Ruvidar的能力TM是一種非常穩定的小分子,能夠在8年內保持其效力和純度,而不會有明顯的降解。這將使我們的臨床合作夥伴能夠在多年內採購和存儲我們的PDC技術,而不會損失臨床性能,從而最大限度地減少隨著時間的推移處置/更換未使用的藥物的要求。“

Mr. Roger DuMoulin-White, BSc, P.Eng, Pro.Dir, President and Chief Executive Officer of Theralase stated, "Since 2015, Theralase has utilized the services of an external, independent testing laboratory to conduct accelerated aging and real time stability studies in the storage of RuvidarTM, with the goal of validating product purity and hence efficacy over time. The recent stability report validates the storage of RuvidarTM over 8 years, providing Theralase additional support that it's lead drug can be successfully manufactured and sterilized, then subsequently stored at clinical study sites around the globe for many years. This extended shelf life allows our future commercial partners to be confident in the ability to procure and store our lead drug without risk of degradation of clinical performance over time. This will significantly reduce the cost of replacement of the drug due to spoilage / lack of efficacy. As a result of the latest report, Theralase will continue to leverage our expertise in the research and development of new PDC formulations, such as Rutherrin, to allow our anti-cancer technology to be available for additional cancer indications."

羅傑·杜穆林-懷特先生,BSC,P.Eng,Pro.Dir,總裁先生和Theralase首席執行官表示,自2015年以來,Theralase一直利用外部獨立測試實驗室的服務來進行Ruvidar存儲的加速老化和即時穩定性研究TM,目標是驗證產品純度,從而隨著時間的推移而發揮功效。最近的穩定性報告證實了Ruvidar的存儲TM在8年多的時間裡,為Theralase提供額外的支持,使其先導藥物能夠成功製造和消毒,然後在全球各地的臨床研究地點儲存多年。延長的保質期使我們未來的商業合作夥伴有信心有能力採購和儲存我們的先導藥物,而不會隨著時間的推移而出現臨床表現退化的風險。這將大大減少因變質/無效而更換藥物的成本。作為最新報告的結果,Theralase將繼續利用我們在研究和開發新的PDC配方(如Rutherrin)方面的專業知識,使我們的抗癌技術可用於更多的癌症適應症。“

About Theralase Technologies Inc.:
Theralase is a clinical stage pharmaceutical company dedicated to the research and development of light and radiation activated compounds, their associated drug formulations and the light systems that activate them, with a primary objective of efficacy and a secondary objective of safety in the destruction of various cancers, bacteria and viruses.

關於Theralase技術公司:
Theralase是一家臨床階段的製藥公司,致力於研究和開發光和輻射激活的化合物、它們的相關藥物配方和激活它們的光系統,主要目標是療效,次要目標是銷毀各種癌症、細菌和病毒的安全性。

Additional information is available at and

欲瞭解更多資訊,請訪問和

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

多倫多證券交易所風險交易所及其監管服務提供商(該術語在多倫多證券交易所的政策中定義)均不對本新聞稿的充分性或準確性承擔責任。

Forward Looking Statements

前瞻性陳述

This news release contains Forward-Looking Statements ("FLS") within the meaning of applicable Canadian securities laws. Such statements include, but are not limited to, statements regarding the Company's proposed development plans with respect to Photo Dynamic Compounds ("PDCs") and their drug formulations. FLS may be identified by the use of the words "may, "should", "will", "anticipates", "believes", "plans", "expects", "estimate", "potential for" and similar expressions; including, statements related to the current expectations of the Company's management for future research, development and commercialization of the Company's PDCs and their drug formulations; including: preclinical research, clinical studies and development and regulatory approvals.

本新聞稿包含前瞻性陳述(“FLS)適用的加拿大證券法所指的範圍內。此類陳述包括但不限於,關於本公司關於照片動態化合物的擬議發展計劃的陳述(PDC“)和他們的藥物配方。FLS可以通過使用單字”可能,“應該“,”將要“,”預期“,”vbl.相信,相信“,”平面圖“,”期望“,”估算“,”潛在的以及類似的表述;包括與公司管理層目前對公司PDC及其藥物配方的未來研究、開發和商業化的期望有關的陳述;包括:臨床前研究、臨床研究和開發以及監管批准。

These statements involve significant risks, uncertainties and assumptions; including, whether the Company is able to: adequately fund and secure the requisite regulatory approvals to successfully complete preclinical and clinical studies in a timely fashion to implement its development plan; successfully commercialize its drug formulations; access sufficient capital to fund the Company's operations, which may not be available on terms that are commercially favorable to the Company or at all; provide preclinical and clinical support that the Company's drug formulations are effective against the conditions tested in its preclinical and clinical studies; comply with the term of license agreements with third parties, not to lose the right to use key intellectual property in its business; protect its intellectual property and the timing and success of this intellectual property and achieve acceptance and approval of regulatory filings. Many of these factors that will determine actual results are beyond the Company's ability to control or predict.

這些陳述涉及重大風險、不確定因素和假設,包括公司是否能夠:提供足夠的資金並獲得必要的監管批准,以及時成功完成臨床前和臨床研究,以實施其開發計劃;成功地將其藥物配方商業化;獲得足夠的資本為公司的運營提供資金,而這些資金可能無法以對公司有利或根本不利於商業的條款提供;提供臨床前和臨床支持,以確保公司的藥物配方對其臨床前和臨床研究中測試的條件有效;遵守與第三方的許可協定條款,不會失去在其業務中使用關鍵知識產權的權利;保護其知識產權和這一知識產權的時機和成功,並實現對監管備案的接受和批准。其中許多將決定實際結果的因素超出了公司的控制或預測能力。

Readers should not unduly rely on these FLS, which are not a guarantee of future performance. There can be no assurance that FLS will successfully come to fruition, and as such, FLS involve known and unknown risks, uncertainties and other factors which may cause actual results or future events to differ materially from the FLS.

讀者不應過度依賴這些FL,它們不能保證未來的表現。不能保證自由貿易協定將成功實現,因此,自由貿易協定涉及已知和未知的風險、不確定因素和其他可能導致實際結果或未來事件與自由貿易協定大不相同的因素。

Although the FLS contained in the press release are based upon what management currently believes to be reasonable assumptions, the Company cannot assure prospective investors that actual results, performance or achievements will be consistent with these FLS.

儘管新聞稿中包含的財務會計準則是基於管理層目前認為合理的假設,但公司不能向潛在投資者保證實際結果、業績或成就將與這些財務會計準則一致。

All FLS are made as of the date hereof and are subject to change. Except as required by law, the Company assumes no obligation to update such statements.

所有FLS均自本合同生效之日起生效,並可隨時更改。除法律另有規定外,本公司不承擔更新此類聲明的義務。

For More Information:
1.866.THE.LASE (843.5273)
416.699.LASE (5273)

有關詳細資訊,請訪問:
1.866.THE.LASE(843.5273)
416.699.LASE(5273)

Kristina Hachey, CPA
Chief Financial Officer
khachey@theralase.com
416.699.LASE (5273) x 224

克裡斯蒂娜·哈奇,註冊會計師
首席財務官
郵箱:khaceh@theralase.com
416.699.LASE(5273)x 224

SOURCE: Theralase Technologies Inc.

資料來源:Theralase Technologies Inc.


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