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Chimerix Announces Closing Of TEMBEXA Sale To Emergent BioSolutions; $238M In Upfront Payment Received At Closing With Additional $136.5M In Potential Milestone Payments Plus Royalties
Chimerix Announces Closing Of TEMBEXA Sale To Emergent BioSolutions; $238M In Upfront Payment Received At Closing With Additional $136.5M In Potential Milestone Payments Plus Royalties
DURHAM, N.C., Sept. 26, 2022 (GLOBE NEWSWIRE) -- Chimerix, Inc. (NASDAQ:CMRX), a biopharmaceutical company whose mission is to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases, today announced the closing of its sale of TEMBEXA to Emergent BioSolutions Inc. (EBS or Emergent).
"The closing of our sale of TEMBEXA to Emergent allows Chimerix to accelerate the value of this product while still participating in its longer-term potential. As we look ahead, our balance sheet is enhanced significantly to support the ongoing development of our oncology franchise. This includes ONC201 which has demonstrated durable responses and an attractive safety profile in a genetically defined population of patients with H3 K27M mutant high-grade glioma. This would represent the first approved therapy specifically targeting patients with this invariably lethal disease," said Mike Sherman, Chief Executive Officer of Chimerix.
EBS paid Chimerix $238 million at closing. The closing amount was subject to the terms of the agreement executed between Biomedical Advanced Research and Development Authority (BARDA) and Chimerix for the procurement of TEMBEXA. Additional future economics from the transaction include:
- Potential milestone payments of up to $124 million (up to $31 million for each of the remaining BARDA procurement options, due within 30 days of exercise);
- 15% royalty on gross profit from sales of TEMBEXA outside the U.S.;
- 20% royalty on gross profit from sales of TEMBEXA in the U.S. that are in excess of 1.7 million treatment courses; and
- Up to an additional $12.5 million upon achievement of certain developmental milestones.
Development and procurement of TEMBEXA have been supported in part with federal funds from BARDA, in the Administration for Strategic Preparedness and Response in the Department of Health and Human Services under Contracts HHSO100201100013C and 75A50122C00047.
DURHAM, N.C., Sept. 26, 2022 (GLOBE NEWSWIRE) -- Chimerix, Inc. (NASDAQ:CMRX), a biopharmaceutical company whose mission is to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases, today announced the closing of its sale of TEMBEXA to Emergent BioSolutions Inc. (EBS or Emergent).
北卡羅來納州達勒姆,9月2022年2月26日(環球網)--生物製藥公司Chimerix,Inc.(納斯達克代碼:CMRX)的使命是開發有意義地改善和延長面臨致命疾病的患者的生命的藥物,該公司今天宣佈完成將TEMBEXA出售給Emergent BioSolutions Inc.(EBS或Emergent)。
"The closing of our sale of TEMBEXA to Emergent allows Chimerix to accelerate the value of this product while still participating in its longer-term potential. As we look ahead, our balance sheet is enhanced significantly to support the ongoing development of our oncology franchise. This includes ONC201 which has demonstrated durable responses and an attractive safety profile in a genetically defined population of patients with H3 K27M mutant high-grade glioma. This would represent the first approved therapy specifically targeting patients with this invariably lethal disease," said Mike Sherman, Chief Executive Officer of Chimerix.
Chimerix首席執行官Mike·謝爾曼表示:“我們將TEMBEXA出售給Emergent的交易完成後,Chimerix可以加快這一產品的價值,同時仍能參與其長期潛力。展望未來,我們的資產負債表將顯著增強,以支持我們腫瘤專營權的持續發展。其中包括ONC201,它已經在H3 K27M突變的高級別膠質瘤患者中展示了持久的反應和誘人的安全性。這將是第一種專門針對這種始終致命的疾病患者的已獲批准的治療方法,”Chimerix首席執行官Mike表示。
EBS paid Chimerix $238 million at closing. The closing amount was subject to the terms of the agreement executed between Biomedical Advanced Research and Development Authority (BARDA) and Chimerix for the procurement of TEMBEXA. Additional future economics from the transaction include:
EBS在交易結束時向Chimerix支付了2.38億美元。最後成交金額取決於生物醫學高級研究和發展局(BARDA)與Chimerix簽署的TEMBEXA採購協議的條款。這筆交易帶來的其他未來經濟效益包括:
- Potential milestone payments of up to $124 million (up to $31 million for each of the remaining BARDA procurement options, due within 30 days of exercise);
- 15% royalty on gross profit from sales of TEMBEXA outside the U.S.;
- 20% royalty on gross profit from sales of TEMBEXA in the U.S. that are in excess of 1.7 million treatment courses; and
- Up to an additional $12.5 million upon achievement of certain developmental milestones.
- 可能的里程碑付款,最高可達1.24億美元(剩餘的BARDA採購選項,每項付款最高可達3100萬美元,應在行使後30天內支付);
- 對TEMBEXA在美國以外地區的銷售毛利潤徵收15%的特許權使用費;
- 對TEMBEXA在美國銷售超過170萬療程的毛利潤徵收20%的特許權使用費;以及
- 在實現某些發展里程碑的情況下,最高可額外獲得1250萬美元。
Development and procurement of TEMBEXA have been supported in part with federal funds from BARDA, in the Administration for Strategic Preparedness and Response in the Department of Health and Human Services under Contracts HHSO100201100013C and 75A50122C00047.
根據合同HHSO100201100013C和75A50122C00047,TEMBEXA的開發和採購部分得到了BARDA、衞生與公眾服務部戰略準備和反應管理局的聯邦資金的支持。
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moomoo是Moomoo Technologies Inc.公司提供的金融資訊和交易應用程式。
在美國,moomoo上的投資產品和服務由Moomoo Financial Inc.提供,一家受美國證券交易委員會(SEC)監管的持牌主體。 Moomoo Financial Inc.是金融業監管局(FINRA)和證券投資者保護公司(SIPC)的成員。
在新加坡,moomoo上的投資產品和服務是通過Moomoo Financial Singapore Pte. Ltd.提供,該公司受新加坡金融管理局(MAS)監管(牌照號碼︰CMS101000) ,持有資本市場服務牌照 (CMS) ,持有財務顧問豁免(Exempt Financial Adviser)資質。本內容未經新加坡金融管理局的審查。
在澳大利亞,moomoo上的金融產品和服務是通過Futu Securities (Australia) Ltd提供,該公司是受澳大利亞證券和投資委員會(ASIC)監管的澳大利亞金融服務許可機構(AFSL No. 224663)。請閱讀並理解我們的《金融服務指南》、《條款與條件》、《隱私政策》和其他披露文件,這些文件可在我們的網站 https://www.moomoo.com/au中獲取。
在加拿大,透過moomoo應用程式提供的僅限訂單執行的券商服務由Moomoo Financial Canada Inc.提供,並受加拿大投資監管機構(CIRO)監管。
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