DermTech (NASDAQ:DMTK – Get Rating) and Viridian Therapeutics (NASDAQ:VRDN – Get Rating) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their profitability, earnings, risk, valuation, institutional ownership, dividends and analyst recommendations.
Insider and Institutional Ownership
75.1% of DermTech shares are held by institutional investors. 3.6% of DermTech shares are held by company insiders. Comparatively, 4.5% of Viridian Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.
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Valuation & Earnings
This table compares DermTech and Viridian Therapeutics' gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio |
| DermTech | $11.84 million | 14.49 | -$78.33 million | ($3.56) | -1.60 |
| Viridian Therapeutics | $2.96 million | 226.72 | -$79.41 million | ($4.61) | -5.11 |
DermTech has higher revenue and earnings than Viridian Therapeutics. Viridian Therapeutics is trading at a lower price-to-earnings ratio than DermTech, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares DermTech and Viridian Therapeutics' net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets |
| DermTech | -748.29% | -49.02% | -43.48% |
| Viridian Therapeutics | -10,981.32% | -206.72% | -50.48% |
Volatility & Risk
DermTech has a beta of 1.4, indicating that its share price is 40% more volatile than the S&P 500. Comparatively, Viridian Therapeutics has a beta of 1.13, indicating that its share price is 13% more volatile than the S&P 500.
Analyst Ratings
This is a breakdown of recent recommendations and price targets for DermTech and Viridian Therapeutics, as provided by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score |
| DermTech | 0 | 1 | 3 | 0 | 2.75 |
| Viridian Therapeutics | 0 | 0 | 6 | 0 | 3.00 |
DermTech presently has a consensus target price of $19.33, indicating a potential upside of 238.59%. Viridian Therapeutics has a consensus target price of $40.20, indicating a potential upside of 70.48%. Given DermTech's higher possible upside, equities research analysts plainly believe DermTech is more favorable than Viridian Therapeutics.
Summary
DermTech beats Viridian Therapeutics on 10 of the 14 factors compared between the two stocks.
About DermTech
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DermTech, Inc., a molecular diagnostic company, develops and markets novel non-invasive genomics tests to diagnosis skin cancer, inflammatory diseases, and aging-related conditions in the United States. It offers DermTech Melanoma Test (DMT), a gene expression test that enhances early detection of genomic atypia and helps rule out melanoma and the need for a surgical biopsy of atypical pigmented lesions. The company also provides adhesive skin sample collection kits, as well as gene expression assays for the Th1, Th2, IFN-gamma, and Th17 inflammatory pathways. In addition, it is developing UV damage DNA risk assessment products, as well as non-melanoma skin cancer diagnostic and cutaneous T-cell lymphoma rule out test products, as well as offering health-related and information services through electronic information and telecommunication technologies. The company sells its products primarily to pathology and oncology practitioners. DermTech, Inc. is headquartered in La Jolla, California.
About Viridian Therapeutics
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Viridian Therapeutics, Inc., a biotechnology company, develops treatments for patients suffering from serious diseases. It develops VRDN-001, a humanized monoclonal anti-IGF-1R antibody that is in Phase 1/2 clinical trial for the treatment of thyroid eye disease (TED); VRDN-002, an IGF-1R antibody, which is in Phase 1 clinical trial; and VRDN-003, a therapeutic antibody targeting IGF-1R for the treatment of TED. The company was formerly known as Miragen Therapeutics, Inc. and changed its name to Viridian Therapeutics, Inc. in January 2021. Viridian Therapeutics, Inc. was founded in 2006 and is headquartered in Waltham, Massachusetts.
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