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Neuropathix, Inc. CEO Issues New Letter to Shareholders; Updates Market on Milestones in Research and Funding

Neuropathix, Inc. CEO Issues New Letter to Shareholders; Updates Market on Milestones in Research and Funding

Neuropathix公司首席执行官向股东发出新信;向市场通报研究和资金方面的最新里程碑
Accesswire ·  2022/04/06 09:06

DOYLESTOWN, PA / ACCESSWIRE / April 6, 2022 / Neuropathix, Inc. ("Neuropathix" or the "Company") (OTCQB:NPTX), a socially responsible pain management life sciences company, announced today that its CEO Dean Petkanas has issued a letter to its shareholders, providing commentary on the Company's recently achieved milestones, updates on its research and financial positioning. Please see the contents of the letter below including a summary.

宾夕法尼亚州多伊尔斯敦/ACCESSWIRE/2022年4月6日/具有社会责任感的疼痛管理生命科学公司Neuropathix,Inc.(“Neuropathix”或“公司”)(场外交易市场代码:NPTX)今天宣布,其首席执行官迪恩·佩特卡纳斯已致信股东,就公司最近取得的里程碑、研究和财务定位的最新情况发表评论。请看下面这封信的内容,包括摘要。

Summary:

摘要:

  • Neuropathix continues to experience shareholder base growth and further support from long-term investors, including a recent bridge financing.
  • In the past decade, pharmaceutical companies have been reluctant to re-address pain treatments following the opioids crisis. However, we see a change on the horizon.
  • Neuropathix has designated proprietary, cannabinoid-derivative compound KLS-13019 as lead drug candidate for the treatment of neuropathic pain, a viable alternative to opioids.
  • Neuropathix wholly owned subsidiary, Kannalife Sciences, Inc. received a $2.97 million grant from the National Institutes of Health HEAL program for IND enabling studies and the furtherment of its clinical program for KLS-13019.
  • The NIH grant was awarded based on a priority impact score of 20 by peer reviewing scientists, denoting the exceptional and novel potential of KLS-13019's non-addictive properties seen through advanced pre-clinical studies for the treatment of chemotherapy induced peripheral neuropathy (CIPN).
  • Neuropathix continues to move forward in preparation of an IND filing for the use of KLS-13019 in CIPN. The next two major steps in 2022 will be the successful completion of the first leg of commercial scale up and a drug discrimination study in animals.
  • Year two of the grant funding should enable the Company to move KLS-13019 into animal toxicity studies by early 2023, as the next steps towards IND submission with the US FDA.
  • Neuropathix继续经历股东基础的增长和长期投资者的进一步支持,包括最近的过渡性融资。
  • 在过去的十年里,制药公司在阿片类药物危机之后一直不愿重新解决疼痛治疗问题。然而,我们看到了地平线上的变化。
  • Neuropathix已指定专有大麻素衍生物化合物KLS-13019作为治疗神经病理性疼痛的主要候选药物,这是阿片类药物的可行替代品。
  • Neuropathix的全资子公司KannaLife Science,Inc.从美国国立卫生研究院获得297万美元的赠款,用于IND使能研究和进一步推进其针对KLS-13019的临床计划。
  • 美国国立卫生研究院的拨款是基于同行评审科学家的20分优先影响评分授予的,这表明了KLS-13019的非成瘾特性的特殊和新的潜力,通过用于治疗化疗引起的周围神经病变的高级临床前研究看到了这一潜力。
  • Neuropathix继续向前推进,准备在CIPN中使用KLS-13019的IND申请。2022年的下两个主要步骤将是成功完成商业放大的第一阶段和在动物身上进行药物歧视研究。
  • 第二年的赠款资金将使该公司能够在2023年初将KLS-13019纳入动物毒性研究,作为向美国食品和药物管理局提交IND的下一步。

To read the Letter to Shareholders in full, please visit:

要阅读致股东的信的全文,请访问:

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke (NINDS) of the National Institutes of Health (NIH) under Award Number R42NS120548.

本出版物中报道的研究由美国国立卫生研究院(NIH)的国家神经疾病和中风研究所(NINDS)支持,获奖号为R42NS120548。

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

内容完全由作者负责,不一定代表美国国立卫生研究院的官方观点。

About KLS-13019

关于KLS-13019

KLS-13019 is Neuropathix patented lead clinical compound for the potential treatment of a range of inflammatory, neurodegenerative and neuropathic pain disorders, beginning with chemotherapy-induced peripheral neuropathy (CIPN). KLS-13019 is a monotherapeutic non-opioid cannabinoid derivative that has been shown to prevent and reverse neuropathic pain in pre-clinical animal studies. KLS-13019 has not been reviewed or approved for patient use by the U.S. Food and Drug Administration (FDA) or any other healthcare authority in the world. Its safety and efficacy have not been confirmed by FDA-approved research.

KLS-13019是Neuropathix获得专利的领先临床化合物,用于潜在地治疗一系列炎性、神经退行性和神经病理性疼痛疾病,从化疗引起的周围神经病变开始。KLS-13019是一种单一治疗的非阿片类大麻衍生物,在临床前动物研究中已被证明可以预防和逆转神经病理性疼痛。KLS-13019尚未经过美国食品和药物管理局或世界上任何其他医疗机构的审查或批准用于患者。其安全性和有效性尚未得到FDA批准的研究的证实。

About Neuropathix, Inc.

关于Neuropathix公司

Neuropathix is a biopharmaceutical company focused on the research and development of a pipeline of next generation, socially responsible pain management and neuroprotective therapeutics to treat patients with significant unmet medical needs. Over the past ten years, Neuropathix has discovered, developed, and patented a global intellectual property estate, led by its lead clinical target, KLS-13019, as novel, new therapeutic agents designed to prevent and reverse neuropathic pain, reduce oxidative stress, and act as anti-inflammatory neuroprotectants. The Company's family of patented monotherapeutic molecules focuses on treating oxidative stress-related diseases, chronic pain management, and neurodegenerative disorders. The therapeutic targets include chemotherapy-induced peripheral neuropathy (CIPN), a chronic neuropathy caused by toxic chemotherapeutic agents; hepatic encephalopathy (HE), a neurotoxic brain-liver disorder caused by excessive concentrations of ammonia and ethanol in the brain; mild traumatic brain injury (mTBI), a disorder associated with single and repetitive impact injuries; and chronic traumatic encephalopathy (CTE), a disease associated with highly repetitive impact injuries in professional and amateur sports. Neuropathix conducts its research and development efforts at the Pennsylvania Biotechnology Center of Bucks County in Doylestown, PA. For more information about Neuropathix, visit and the Company's Twitter page at @neuropathix.

Neuropathix是一家生物制药公司,专注于研究和开发下一代、对社会负责的疼痛管理和神经保护疗法的管道,以治疗有重大未得到满足的医疗需求的患者。在过去的十年里,Neuropathix已经发现、开发和申请了全球知识产权,以其主要临床目标KLS-13019为首,作为新型治疗药物,旨在预防和逆转神经病理性疼痛,减少氧化应激,并作为抗炎神经保护剂。该公司的专利单一治疗分子系列专注于治疗氧化应激相关疾病、慢性疼痛管理和神经退行性疾病。治疗的目标包括化疗所致的周围神经病(CIPN),这是一种由有毒化疗药物引起的慢性神经病变;肝性脑病(HE),一种因脑内氨和乙醇浓度过高而引起的神经毒性脑-肝疾病;轻度创伤性脑损伤(MTBI),一种与单次和重复撞击损伤有关的疾病;以及慢性创伤性脑病(CTE),一种与职业和业余运动中高度重复的撞击损伤有关的疾病。Neuropathix在宾夕法尼亚州多伊尔斯敦的巴克斯县宾夕法尼亚州生物技术中心进行研究和开发工作。欲了解有关Neuropathix的更多信息,请访问网站和该公司的推特页面:@Neuropathix。

Forward-Looking Statements

前瞻性陈述

This press release may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and is subject to the Safe Harbor created by those sections. This press release contains statements about expected future events, the Company's business plan, plan of operations, the viability of the Company's drug candidates, the targeted beneficial effects of KLS-13019, the Company's position, and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements, by definition, involve risks and uncertainties. The Company does not sell or distribute any products that are in violation of the United States Controlled Substances Act.

本新闻稿可能包含1933年证券法第27A节和1934年证券交易法第21E节所界定的某些前瞻性陈述和信息,并受这两节所创造的安全港的约束。本新闻稿包含有关预期的未来事件、公司的业务计划、运营计划、公司候选药物的可行性、KLS-13019的目标有益效果、公司的状况和/或财务结果的陈述,这些陈述具有前瞻性,受风险和不确定因素的影响。根据定义,此类前瞻性陈述包含风险和不确定因素。本公司不销售或分销任何违反《美国管制物质法》的产品。

CONTACTS:

联系人:

Public Relations:
Kyle Porter
CMW Media
P: 858-221-8001
E: nptx@cmwmedia.com

公共关系:
凯尔·波特
CMW媒体
P: 858-221-8001
邮箱:nptx@cmwmedia.com

Investor Relations:
Louie Toma
Managing Director
CORE IR
P: 516-222-2560
E: louie@coreir.com

投资者关系:
路易·托马
经营董事
核心红外光谱
P: 516-222-2560
E:Louie@coreir.com

SOURCE: Neuropathix, Inc.

资料来源:Neuroath,Inc.


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