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Chimerix Announces Closing Of TEMBEXA Sale To Emergent BioSolutions; $238M In Upfront Payment Received At Closing With Additional $136.5M In Potential Milestone Payments Plus Royalties
Chimerix Announces Closing Of TEMBEXA Sale To Emergent BioSolutions; $238M In Upfront Payment Received At Closing With Additional $136.5M In Potential Milestone Payments Plus Royalties
DURHAM, N.C., Sept. 26, 2022 (GLOBE NEWSWIRE) -- Chimerix, Inc. (NASDAQ:CMRX), a biopharmaceutical company whose mission is to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases, today announced the closing of its sale of TEMBEXA to Emergent BioSolutions Inc. (EBS or Emergent).
"The closing of our sale of TEMBEXA to Emergent allows Chimerix to accelerate the value of this product while still participating in its longer-term potential. As we look ahead, our balance sheet is enhanced significantly to support the ongoing development of our oncology franchise. This includes ONC201 which has demonstrated durable responses and an attractive safety profile in a genetically defined population of patients with H3 K27M mutant high-grade glioma. This would represent the first approved therapy specifically targeting patients with this invariably lethal disease," said Mike Sherman, Chief Executive Officer of Chimerix.
EBS paid Chimerix $238 million at closing. The closing amount was subject to the terms of the agreement executed between Biomedical Advanced Research and Development Authority (BARDA) and Chimerix for the procurement of TEMBEXA. Additional future economics from the transaction include:
- Potential milestone payments of up to $124 million (up to $31 million for each of the remaining BARDA procurement options, due within 30 days of exercise);
- 15% royalty on gross profit from sales of TEMBEXA outside the U.S.;
- 20% royalty on gross profit from sales of TEMBEXA in the U.S. that are in excess of 1.7 million treatment courses; and
- Up to an additional $12.5 million upon achievement of certain developmental milestones.
Development and procurement of TEMBEXA have been supported in part with federal funds from BARDA, in the Administration for Strategic Preparedness and Response in the Department of Health and Human Services under Contracts HHSO100201100013C and 75A50122C00047.
DURHAM, N.C., Sept. 26, 2022 (GLOBE NEWSWIRE) -- Chimerix, Inc. (NASDAQ:CMRX), a biopharmaceutical company whose mission is to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases, today announced the closing of its sale of TEMBEXA to Emergent BioSolutions Inc. (EBS or Emergent).
北卡罗来纳州达勒姆,9月2022年2月26日(环球网)--生物制药公司Chimerix,Inc.(纳斯达克代码:CMRX)的使命是开发有意义地改善和延长面临致命疾病的患者的生命的药物,该公司今天宣布完成将TEMBEXA出售给Emergent BioSolutions Inc.(EBS或Emergent)。
"The closing of our sale of TEMBEXA to Emergent allows Chimerix to accelerate the value of this product while still participating in its longer-term potential. As we look ahead, our balance sheet is enhanced significantly to support the ongoing development of our oncology franchise. This includes ONC201 which has demonstrated durable responses and an attractive safety profile in a genetically defined population of patients with H3 K27M mutant high-grade glioma. This would represent the first approved therapy specifically targeting patients with this invariably lethal disease," said Mike Sherman, Chief Executive Officer of Chimerix.
Chimerix首席执行官Mike·谢尔曼表示:“我们将TEMBEXA出售给Emergent的交易完成后,Chimerix可以加快这一产品的价值,同时仍能参与其长期潜力。展望未来,我们的资产负债表将显著增强,以支持我们肿瘤专营权的持续发展。其中包括ONC201,它已经在H3 K27M突变的高级别胶质瘤患者中展示了持久的反应和诱人的安全性。这将是第一种专门针对这种始终致命的疾病患者的已获批准的治疗方法,”Chimerix首席执行官Mike表示。
EBS paid Chimerix $238 million at closing. The closing amount was subject to the terms of the agreement executed between Biomedical Advanced Research and Development Authority (BARDA) and Chimerix for the procurement of TEMBEXA. Additional future economics from the transaction include:
EBS在交易结束时向Chimerix支付了2.38亿美元。最后成交金额取决于生物医学高级研究和发展局(BARDA)与Chimerix签署的TEMBEXA采购协议的条款。这笔交易带来的其他未来经济效益包括:
- Potential milestone payments of up to $124 million (up to $31 million for each of the remaining BARDA procurement options, due within 30 days of exercise);
- 15% royalty on gross profit from sales of TEMBEXA outside the U.S.;
- 20% royalty on gross profit from sales of TEMBEXA in the U.S. that are in excess of 1.7 million treatment courses; and
- Up to an additional $12.5 million upon achievement of certain developmental milestones.
- 可能的里程碑付款,最高可达1.24亿美元(剩余的BARDA采购选项,每项付款最高可达3100万美元,应在行使后30天内支付);
- 对TEMBEXA在美国以外地区的销售毛利润征收15%的特许权使用费;
- 对TEMBEXA在美国销售超过170万疗程的毛利润征收20%的特许权使用费;以及
- 在实现某些发展里程碑的情况下,最高可额外获得1250万美元。
Development and procurement of TEMBEXA have been supported in part with federal funds from BARDA, in the Administration for Strategic Preparedness and Response in the Department of Health and Human Services under Contracts HHSO100201100013C and 75A50122C00047.
根据合同HHSO100201100013C和75A50122C00047,TEMBEXA的开发和采购部分得到了BARDA、卫生与公众服务部战略准备和反应管理局的联邦资金的支持。
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在美国,moomoo上的投资产品和服务由Moomoo Financial Inc.提供,一家受美国证券交易委员会(SEC)监管的持牌主体。 Moomoo Financial Inc.是金融业监管局(FINRA)和证券投资者保护公司(SIPC)的成员。
在新加坡,moomoo上的投资产品和服务是通过Moomoo Financial Singapore Pte. Ltd.提供,该公司受新加坡金融管理局(MAS)监管(牌照号码︰CMS101000) ,持有资本市场服务牌照 (CMS) ,持有财务顾问豁免(Exempt Financial Adviser)资质。本内容未经新加坡金融管理局的审查。
在澳大利亚,moomoo上的金融产品和服务是通过Futu Securities (Australia) Ltd提供,该公司是受澳大利亚证券和投资委员会(ASIC)监管的澳大利亚金融服务许可机构(AFSL No. 224663)。请阅读并理解我们的《金融服务指南》、《条款与条件》、《隐私政策》和其他披露文件,这些文件可在我们的网站 https://www.moomoo.com/au中获取。
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