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IGC Announced Issuance of Second Patent for the Treatment of Alzheimer's Using THC

IGC Announced Issuance of Second Patent for the Treatment of Alzheimer's Using THC

IGC宣布颁发使用THC治疗阿尔茨海默氏症的第二项专利
Benzinga Real-time News ·  2022/09/21 06:04

India Globalization Capital, Inc. ("IGC" or the "Company") (NYSE:IGC) announced today that the United States Patent and Trademark Office ("USPTO") issued a second patent (#11,446,276) for the treatment of Alzheimer's disease entitled "Extreme low dose THC as a therapeutic and prophylactic agent for Alzheimer's disease." The original patent application was initiated by the University of South Florida ("USF") and filed on July 30, 2015. On May 25, 2017, IGC entered into an exclusive license agreement with USF with respect to the patent application and the associated research conducted on Alzheimer's disease. On January 9, 2020, the patent application was modified by the Company. Separately, on July 22, 2021, IGC announced the grant of the first patent (11,065,225) for some of that research and work. This new patent is for a continuation of that work. The Company's subsidiary, IGC Pharma, used some of the research to develop an oral formulation, IGC-AD1. Based on the USF research on Alzheimer's cell lines, subject to further testing and clinical trials, testing indicates that on a dose dependent manner, the active agents in IGC-AD1 may ameliorate Aß plaque and decrease ptau, a phosphorylated protein responsible for tangles in neurons. Plaques and tangles are key hallmarks of Alzheimer's disease. Further, testing in an Alzheimer's mouse model showed that it improved memory as demonstrated in a Morris Water Maze te

亚洲网加利福尼亚州圣克拉拉10月24日电印度全球化资本公司(以下简称“IGC”或“公司”)(纽约证券交易所市场代码:IGC)今天宣布,美国专利商标局(“USPTO”)为治疗阿尔茨海默病颁发了第二项专利(#11,446,276),题为“极低剂量的THC作为阿尔茨海默病的治疗和预防药物”。最初的专利申请是由南佛罗里达大学(USF)发起的,并于2015年7月30日提交。2017年5月25日,IGC与美国联邦就阿尔茨海默病的专利申请和相关研究达成独家许可协议。2020年1月9日,该专利申请被公司修改。另外,2021年7月22日,IGC宣布为其中一些研究和工作授予第一项专利(11,065,225项)。这项新专利是为了继续这项工作。该公司的子公司IGC Pharma利用一些研究开发了一种口服制剂IGC-AD1。基于USF对阿尔茨海默氏症细胞系的研究,进一步的测试和临床试验表明,IGC-AD1中的激活剂以一种剂量依赖的方式可以改善A?斑块并降低ptau,ptau是一种导致神经元缠结的磷酸化蛋白。斑块和缠结是阿尔茨海默病的主要特征。此外,在阿尔茨海默氏症小鼠模型中的测试表明,它改善了记忆,这在莫里斯水迷宫TE中得到了证明

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