Merck & Co Stock Forum

Producer price index, a measure of inflation at wholesale level, increased 0.2%. This is less than the 0.3% estimate, which kind of provides some level of relief for the market.
That said, this new set data is still showing that inflation is very sticky. The final mile towards Fed’s 2% is going to be a tough one
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🗓️ Last week’s PDUFAs:
$Akebia Therapeutics(AKBA.US)$ : Approved 🎉
⇒ Vafseo (Vadadustat)
⇒ Anemia due to CKD
⇒ NDA
⇒ PDUFA: 3/27/24
$Merck & Co(MRK.US)$ : Approved 🎉
⇒ WINREVAIR (sotatercept)
⇒ Pulmonary arterial hypertension
⇒ BLA
⇒ PDUFA: 3/26/24
$AstraZeneca(AZN.US)$ : Approved 🎉
⇒ Ultomiris (ravulizumab)
⇒ NMOSD
⇒ sBLA
$Regeneron Pharmaceuticals(REGN.US)$ : CRL 🙁
⇒ Odronextamab
⇒ r/r FL and r/r DLBCL
⇒ BLA
⇒ PDUFA: 3/31/24
📌 This week’s PDUFAs: 🚨
$AstraZeneca(AZN.US)$ : 🤔
⇒...

$SPDR S&P Biotech ETF(XBI.US)$
$Merck & Co(MRK.US)$ x $Immunovant(IMVT.US)$
$Eli Lilly and Co(LLY.US)$ x $Cytokinetics(CYTK.US)$ (and soon)
$Regeneron Pharmaceuticals(REGN.US)$ x $Apellis Pharmaceuticals(APLS.US)$ (panache & brash)
$Gilead Sciences(GILD.US)$ x %$Madrigal Pharmaceuticals(MDGL.US)$ (liver king)
$Bristol-Myers Squibb(BMY.US)$ x $Iovance Biotherapeutics(IOVA.US)$ (cell Tx boost needed)
$Eli Lilly and Co(LLY.US)$ x $Merus(MRUS.US)$ (partner n...

$Merck & Co(MRK.US)$'s $11.5 bil bet on Acceleron in 2021 pays off w/ FDA approval of Wenrevair for PAH,
When deal closed in 2021 analysts were projecting peak sales of $2.2 bil for sotatercept (Wenrevair), now estimates are as high as $5-$7.5 bil,
Looks like MRK got a great deal but Wenrevair would still only cover about 20%-25% of Keytruda's $25 bil in rev from LOE in 2028,
MRK's made 4 other big acquisitions since 2021: $680 mil for $HARP, $610 mil for Caraway, $1.3 bil for Imago and the big...

$Merck & Co(MRK.US)$ FDA Approves WINREVAIR™ (sotatercept-csrk) 🥳
🥇 First-in-class Tx for adults with pulmonary arterial hypertension (PAH WHO Group 1)
📌 significantly improved exercise capacity & multiple important secondary outcome measures
ℹ️ WINREVAIR™
⇒ injection for SC use 💉
⇒ previously granted Breakthrough Therapy Designation
⇒ BLA w/ assigned PDUFA 3/26/24

S&P 500 Opening Bell Heatmap (Mar. 27, 2024)
$SPDR S&P 500 ETF(SPY.US)$ +0.51% 🟩
$Invesco QQQ Trust(QQQ.US)$ +0.54% 🟩
$Dow Jones Industrial Average(.DJI.US)$ +0.67% 🟩
$iShares Russell 2000 ETF(IWM.US)$ +1.01% 🟩
Stocks on move: $Robinhood(HOOD.US)$ +4.5%, $Merck & Co(MRK.US)$ +4.6%, $Disney(DIS.US)$ +1.5%, $Enphase Energy(ENPH.US)$ +4.9%, $Trump Media & Technology(DJT.US)$ +19%, $MicroStrategy(MSTR.US)$ + 5.7%, $Marvell Technology(MRVL.US)$ +4.90%, $nCino(NCNO.US)$ +16%, $Tesla(TSLA.US)$ +0.4% (...

Morning Movers
Gapping up
$Deutsche Bank(DB.US)$ shares rose 3% after Morgan Stanley upgraded the stock to overweight, suggesting further potential growth following a strong performance in 2024.
$Merck & Co(MRK.US)$ stock rose 4.8% after its drug for treating a rare lung disease received FDA approval.
$Trump Media & Technology(DJT.US)$ stock jumped 14%, following gains after its Nasdaq debut.
$Robinhood(HOOD.US)$ stock climbed 6...

Key Takeaway
GameStop ( $GameStop(GME.US)$ ) and Forge Global ( $Forge Global(FRGE.US)$ ) face pre-market declines of 17% and 11% respectively, while Novocure ( $Novocure(NVCR.US)$ ) surges 30% on positive trial results.
Merck ( $Merck & Co(MRK.US)$ ) gains 4% after FDA approval of its treatment, highlighting a day of significant volatility and strategic moves in the U.S. stock market.
A Glimpse into Quarter-End Moves
As the curtains draw near on...