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诺华(NVS.US)超10亿美元囊获Arvinas潜在“best-in-class”蛋白降解剂

Novartis (NVS.US) received Arvinas's potential “best-in-class” proteolytic agent for over $1 billion

Zhitong Finance ·  Apr 11 21:37

Arvinas (ARVN.US) announced that it has reached an exclusive strategic licensing agreement with Novartis/NVS.us (Novartis/NVS.us).

The Zhitong Finance App learned that Arvinas (ARVN.US) announced that it has reached an exclusive strategic licensing agreement with Novartis/NVS.us (Novartis/NVS.us). Novartis will receive up to $1.01 billion to develop and commercialize Arvinas second-generation androgen receptor (AR) targeted protein-degrading chimer (PROTAC) ARV-766 on a global scale. Novartis also obtained AR-v7, another pre-clinical AR-targeted proTAC degrading agent from Arvinas.

Under the terms of the transaction agreement, Novartis will be responsible for the global clinical development and commercialization activities of the ARV-766, and will have all research, development, manufacturing and commercialization rights related to the pre-clinical AR-V7 project. Arvinas will receive a total of $150 million in advance payments. Under the license agreement, Arvinas is eligible for up to $1.01 billion in additional development, regulatory and commercial milestone payments.

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