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亚盛医药-B(06855)三项研究进展亮相2024年美国癌症研究协会年会

Yasheng Pharmaceutical-B (06855) three research advances unveiled at the 2024 American Association for Cancer Research Annual Meeting

Zhitong Finance · Apr 7 19:53

ASCENTAGE-B -2.07%

智通财经APP讯，亚盛医药-B(06855)发布公告，公司在2024年美国癌症研究协会(AACR)年会上公布了三项临床前研究成果，涉及公司原创1类新药奥雷巴替尼(商品名：耐立克)、MDM2-p53抑制剂APG-115、FAK/ALK/ROS1三联酪氨酸激酶抑制剂APG-2449和胚胎外胚层发育蛋白(EED)抑制剂APG-5918四个重要品种。

三项临床前研究成果如下：

新型多靶点酪氨酸激酶抑制剂奥雷巴替尼在SDH缺陷型肿瘤中显示出优异的抗肿瘤作用

胚胎外胚层发育(EED)抑制剂APG-5918(EEDi-5273)联合MDM2 抑制剂 alrizomadlin(APG-115)在前列腺癌(PCa)临床前模型中协同抑制肿瘤生长

新型黏着斑激酶(FAK)抑制剂APG-2449在上皮性卵巢癌(EOC)中可抑制肿瘤细胞的转移并增强聚乙二醇脂质体阿霉素(PLD)的抗肿瘤作用

Zhitong Finance App News, Yasheng Pharmaceutical-B (06855) issued an announcement. The company announced three pre-clinical research results at the 2024 American Association for Cancer Research (AACR) annual meeting, involving the company's original Class 1 drug olevatinib (trade name: Nellick)), MDM2-p53 inhibitor APG-115, FAK/ALK/ROS1 triple tyrosine kinase inhibitor APG-2449, and embryonic ectodermal development protein (EED) inhibitor APG-5918 are important varieties.

The results of the three preclinical studies are as follows:

Orebatinib, a novel multi-target tyrosine kinase inhibitor, shows excellent anti-tumor effects in SDH deficient tumors

Embryonic ectodermal development (EED) inhibitor APG-5918 (eEdi-5273) combined with MDM2 inhibitor alrizomadlin (APG-115) co-inhibits tumor growth in a preclinical model of prostate cancer (PCa)

The novel focal adhesion kinase (FAK) inhibitor APG-2449 inhibits tumor cell metastasis and enhances the antitumor effect of the polyethylene glycol liposome doxorubicin (PLD) in epithelial ovarian cancer (EOC)

Disclaimer: This content is for informational and educational purposes only and does not constitute a recommendation or endorsement of any specific investment or investment strategy. Read more

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This page is machine-translated. Moomoo tries to improve but do not guarantee the accuracy and reliability of the translation, and will not be liable for any loss or damage caused by any inaccuracy or omission of the translation.

This presentation is for informational and educational use only and is not a recommendation or endorsement of any particular investment or investment strategy. Investment information provided in this content is general in nature, strictly for illustrative purposes, and may not be appropriate for all investors. It is provided without respect to individual investors’ financial sophistication, financial situation, investment objectives, investing time horizon, or risk tolerance. You should consider the appropriateness of this information having regard to your relevant personal circumstances before making any investment decisions. Past investment performance does not indicate or guarantee future success. Returns will vary, and all investments carry risks, including loss of principal. Moomoo makes no representation or warranty as to its adequacy, completeness, accuracy or timeline for any particular purpose of the above content.

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