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Promising Preliminary Phase 1 Data and Strong INDUKINE Platform Basis for Buy Rating on Werewolf Therapeutics: A Leerink Partners Analysis
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Promising Preliminary Phase 1 Data and Strong INDUKINE Platform Basis for Buy Rating on Werewolf Therapeutics: A Leerink Partners Analysis

Leerink Partners analyst Daina Graybosch has maintained their bullish stance on HOWL stock, giving a Buy rating yesterday.

Daina Graybosch from Leerink Partners has assigned a Buy rating to Werewolf Therapeutics (ticker: HOWL) for a number of reasons. Firstly, Graybosch believes that the market is not fully appreciating the preliminary Phase 1 solid tumor data for Werewolf’s lead program, WTX-124, which was presented at the recent Society for Immunotherapy of Cancer meeting. Despite being in the early stages, the initial clinical data aligns with the high expectations for WTX-124, indicating a distinctive clinical profile for the drug in treating advanced immunotherapy-sensitive tumors.

Furthermore, the preliminary safety, pharmacokinetic (PK), and biomarker data for WTX-124 provides crucial proof-of-mechanism for Werewolf’s broader INDUKINE platform. Graybosch highlighted that this has positive implications for Werewolf’s earlier-stage INDUKINE pipeline. Graybosch also mentioned that investors are likely waiting for the more comprehensive Phase 1 WTX-124 update in the first half of 2024 for confirmation of the early dose-response relationship with additional patients and dose levels. Given the near-term financing risk and focus on WTX-124, she does not anticipate the WTX-518 product nomination or preclinical INDUKINE updates in general, to generate investor excitement.

In another report released yesterday, H.C. Wainwright also reiterated a Buy rating on the stock with a $15.00 price target.

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Werewolf Therapeutics (HOWL) Company Description:

Werewolf Therapeutics Inc is an innovative biopharmaceutical company pioneering the development of therapeutics engineered to stimulate the body’s immune system for the treatment of cancer.

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