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Newly Listed NewAmsterdam Pharma Touts Encouraging Data From High Cholesterol Treatment

Benzinga Real-time News ·  Jan 17, 2023 12:22
  • NewAmsterdam Pharma Company N.V. (NASDAQ:NAMS) announced topline results from ROSE2 Phase 2 trial evaluating obicetrapib in combination with ezetimibe as an adjunct to high-intensity statin therapy.
  • NewAmsterdam is now selecting a formulated fixed-dose combination tablet of obicetrapib plus ezetimibe, a non-statin oral LDL-lowering therapy, to be tested in a definitive bioequivalence and a Phase 3 safety & efficacy trial.
  • The primary efficacy endpoint for the percent change from Day 1 to Day 84 in LDL-C for the combination treatment group compared to the placebo group was met.
  • Patients treated with the combination of obicetrapib and ezetimibe achieved a median reduction in LDL-C of 59% compared to patients treated with a placebo, who achieved a median reduction in LDL-C of 6%.
  • Overall, the obicetrapib combo therapy was well-tolerated, with a safety profile comparable to a placebo.
  • In November 2022, NewAmsterdam Pharma debuted a public company via a SPAC deal with Frazier Lifesciences Acquisition Corporation.
  • After the transaction, the company held a cash balance of approximately $490 million, which it believes will be sufficient to fund operations through 2026.
  • Price Action: NAMS shares are trading lower by 2.25% at $9.99 on the last check Tuesday.
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