- Data indicate continued clinical responses with an acceptable safety profile in heavily pre-treated patients with late-stage synovial sarcoma after a single dose of afami-cel -
- Overall response rate in synovial sarcoma of 39% by independent review -consistent with previous data -
-Median duration of response of 50 weeks, consistent with previous data -
- Afami-cel drives tumor infiltration of activated and proliferative cytotoxic ("killer") T-cells into tumors - which likely contributes to antitumor response -
- Adaptimmune is on track to initiate a rolling BLA submission for afami-cel for the treatment of synovial sarcoma in Q4 2022 with a target for completion in mid-year 2023 -