The following is a summary of the Nautilus Biotechnology, Inc. (NAUT) Q4 2023 Earnings Call Transcript:

Financial Performance:

• Nautilus Biotechnology reported Q4 operating expenses of $20.0 million, largely driven by increased headcount.

• Research and development expenses were $12.5 million and general and administrative expenses were $7.5 million.

• Net loss for Q4 stood at $17.0 million. For the full fiscal year, operating expenses totaled $76.2 million, marking a 20% increase from the prior year, while the net loss reached $63.7 million.

• The company ended the fiscal year with around $264 million in cash and cash equivalents.

• In 2024, it plans to increase the expenditure in preparation for a Commercial Launch, expecting operating expenses to rise by approximately 25% from 2023 levels.

• The company has filed for a prospectus supplement, hinting at a potential $125 million at-the-market offering for future capital raising.

Business Progress:

• Nautilus has made major progress in its development activities, enhancing the scale, stability, and reproducibility of its consumables.

• It has also advanced its chip and flow cell fabrication and assembly processes, which led to improvements in scaling and reproducibility.

• Nautilus successfully upgraded its software and bioinformatics capabilities for data handling.

• The company, in collaboration with Genentech and Amgen, is conducting targeted proteoform studies to get vital insights into disease biology.

• The firm is preparing the foundational elements necessary for launching its platform ahead in 2024.

• A notably successful project was the expansion of manufacturing throughput and scale for the labeled probes and particle scaffolds— by over ten times.

• The company continues to focus on expanding work with existing collaborators and is eager to share progress updates with the proteomics community, planning to present new data at upcoming conferences.

More details: Nautilus Biotechnology IR

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