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IGC Announced Issuance of Second Patent for the Treatment of Alzheimer's Using THC

IGC Announced Issuance of Second Patent for the Treatment of Alzheimer's Using THC

IGC宣佈頒發使用THC治療阿爾茨海默氏症的第二項專利
Benzinga Real-time News ·  2022/09/21 06:04

India Globalization Capital, Inc. ("IGC" or the "Company") (NYSE:IGC) announced today that the United States Patent and Trademark Office ("USPTO") issued a second patent (#11,446,276) for the treatment of Alzheimer's disease entitled "Extreme low dose THC as a therapeutic and prophylactic agent for Alzheimer's disease." The original patent application was initiated by the University of South Florida ("USF") and filed on July 30, 2015. On May 25, 2017, IGC entered into an exclusive license agreement with USF with respect to the patent application and the associated research conducted on Alzheimer's disease. On January 9, 2020, the patent application was modified by the Company. Separately, on July 22, 2021, IGC announced the grant of the first patent (11,065,225) for some of that research and work. This new patent is for a continuation of that work. The Company's subsidiary, IGC Pharma, used some of the research to develop an oral formulation, IGC-AD1. Based on the USF research on Alzheimer's cell lines, subject to further testing and clinical trials, testing indicates that on a dose dependent manner, the active agents in IGC-AD1 may ameliorate Aß plaque and decrease ptau, a phosphorylated protein responsible for tangles in neurons. Plaques and tangles are key hallmarks of Alzheimer's disease. Further, testing in an Alzheimer's mouse model showed that it improved memory as demonstrated in a Morris Water Maze te

亞洲網加利福尼亞州聖克拉拉10月24日電印度全球化資本公司(以下簡稱“IGC”或“公司”)(紐約證券交易所市場代碼:IGC)今天宣佈,美國專利商標局(“USPTO”)為治療阿爾茨海默病頒發了第二項專利(#11,446,276),題為“極低劑量的THC作為阿爾茨海默病的治療和預防藥物”。最初的專利申請是由南佛羅裏達大學(USF)發起的,並於2015年7月30日提交。2017年5月25日,IGC與美國聯邦就阿爾茨海默病的專利申請和相關研究達成獨家許可協議。2020年1月9日,該專利申請被公司修改。另外,2021年7月22日,IGC宣佈為其中一些研究和工作授予第一項專利(11,065,225項)。這項新專利是為了繼續這項工作。該公司的子公司IGC Pharma利用一些研究開發了一種口服制劑IGC-AD1。基於USF對阿爾茨海默氏症細胞系的研究,進一步的測試和臨牀試驗表明,IGC-AD1中的激活劑以一種劑量依賴的方式可以改善A?斑塊並降低ptau,ptau是一種導致神經元纏結的磷酸化蛋白。斑塊和纏結是阿爾茨海默病的主要特徵。此外,在阿爾茨海默氏症小鼠模型中的測試表明,它改善了記憶,這在莫里斯水迷宮TE中得到了證明

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