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EXCLUSIVE: Takeda's Cancer Partner BridGene Raises $38.5M To Accelerate Work On Undruggable Targets

EXCLUSIVE: Takeda's Cancer Partner BridGene Raises $38.5M To Accelerate Work On Undruggable Targets

獨家報道:武田的癌症合作伙伴Bridgene籌集了3850萬美元,以加快研發無法用藥的靶點
Benzinga Real-time News ·  2022/07/27 06:46

BridGene Biosciences Inc has completed a $38.5 million Series B financing by Lapam Capital, Junson Capital, and Dyee Capital.

Bridgene生物科學公司已經完成了由Lapam Capital、Junson Capital和Dyee Capital進行的3850萬美元的B系列融資。

The platform enables screening small molecules against the whole proteome or a prioritized target in live cells to discover drug candidates for undruggable targets, including cancers.

該平臺能夠針對整個蛋白質組或活細胞中的優先靶點篩選小分子,以發現不可用藥的候選藥物目標,包括癌症。

BridGene's IMTAC can identify hits for targets with shallow binding pockets. BridGene can also identify hits via live cell screening for targets with temporary binding pockets that only form in live cells, such as protein.

Bridgene的IMTAC可以識別綁定口袋較淺的目標。Bridgene還可以通過活細胞篩選具有僅在活細胞中形成的臨時結合口袋的靶點來識別命中,例如蛋白質。

Why It Is Important: The company will use the proceeds to develop its chemoproteomic platform IMTAC.

為什麼它很重要:該公司將利用所得資金開發其化學蛋白質組平臺IMTAC。

The money will also be used to develop BridGene's leading pipeline project, a covalent TEAD inhibitor, and a few other undisclosed oncology pipeline projects based on the IMTAC platform.

這筆資金還將用於開發Bridgene的領先管道項目,一種共價Tead抑制劑,以及基於IMTAC平臺的其他幾個未披露的腫瘤學管道項目。

Last year, the company announced a research collaboration and licensing agreement with Takeda Pharmaceutical Company Limited (NYSE:TAK).

去年,該公司宣佈與以下公司達成研究合作和許可協議武田藥品株式會社(紐約證券交易所股票代碼:Tak)。

The companies will establish up to five drug discovery programs, harnessing BridGene's proprietary IMTAC. Takeda will develop the therapeutic candidates and pursue clinical development. 

兩家公司將建立最多五個藥物發現計劃,利用Bridgene的專利IMTAC。武田將開發治療候選藥物,並致力於臨牀開發。

BridGene is eligible to receive potential milestone payments over $500 million and sales-based royalties.

Bridgene有資格獲得超過5億美元的潛在里程碑付款和基於銷售的特許權使用費。

Price Action: TAK shares closed at $14.55 on Tuesday.

價格行動:週二,德意志銀行的股價收於14.55美元。

声明:本內容僅用作提供資訊及教育之目的,不構成對任何特定投資或投資策略的推薦或認可。 更多信息
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