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SeqLL Announces Formation of Scientific Advisory Board

SeqLL Announces Formation of Scientific Advisory Board

工商局局长宣布成立科学顾问委员会
GlobeNewswire ·  2022/03/21 16:26

BILLERICA, Mass., March 21, 2022 (GLOBE NEWSWIRE) -- SeqLL Inc. ("SeqLL" or the "Company") (NASDAQ: SQL; SQLLW), a technology company providing life sciences instrumentation and research services for collaborative partnerships, today announced the formation of a Scientific Advisory Board ("SAB") comprised of distinguished and world-renowned leaders of the scientific community. The SAB will discuss with management potential new development opportunities that leverage the Company's unique True Single Molecule Sequencing (tSMS®) technology across the "omics" fields, as well as advise management with their existing collaborative, scientific, & development partnerships. Each leader has previously utilized the tSMS platform and will leverage their expertise to provide valuable insight to our company.

马萨诸塞州比勒里卡,2022年3月21日(Global Newswire)--为合作伙伴关系提供生命科学仪器和研究服务的技术公司SeqLL Inc.(以下简称SeqLL或本公司)(纳斯达克代码:SQL;SQLLW)今天宣布成立一个科学顾问委员会,该委员会由科学界杰出的世界知名领袖组成。SAB将与管理层讨论潜在的新发展机会,利用公司在“组学”领域的独特真单分子测序(TSMS®)技术,并与现有的合作、科学和开发伙伴关系向管理层提供建议。每一位领导者之前都使用过TSMS平台,并将利用他们的专业知识为我们的公司提供宝贵的见解。

"We are privileged to be working with this distinguished and talented group of scientific advisors as we expand the reach of our tSMS technology," said Daniel Jones, CEO, President, and Co-Founder of SeqLL. "These advisors bring valuable scientific insight and industry contacts to our work and will assist us in becoming a world-class leader in creating novel assets with our true single molecule sequencing technology."

SeqLL首席执行官、总裁兼联合创始人丹尼尔·琼斯表示:“在我们扩大TSMS技术覆盖范围的过程中,我们很荣幸能与这群杰出而有才华的科学顾问合作。这些顾问为我们的工作带来了宝贵的科学见解和行业联系,并将帮助我们成为用我们真正的单分子测序技术创造新资产的世界级领先者。“

Leaders of the SeqLL Scientific Advisory Board include:

SeqLL科学顾问委员会的领导人包括:

Claes Wahlestedt, M.D., Ph.D., Chairman of the SAB. Director of the Center for Therapeutic Innovation, Leonard M. Miller School of Medicine, University of Miami. Dr. Wahlestedt has a long-standing academic as well as big pharma career in drug discovery, genomics and epigenetics, and has pioneered various translational efforts in these fields. From 2005 to 2011, Dr. Wahlestedt was a professor and a director at The Scripps Research Institute. Prior to that he founded and ran the genomics and bioinformatics center at the Karolinska Institute (a joint venture with Pharmacia/Pfizer). Among companies he has co-founded are CuRNA (now part of Opko Health/Camp4), based on his patent for targeting regulatory noncoding RNAs to up-regulate therapeutic proteins, and Epigenetix Inc., focusing on small molecule drugs for a variety of drug targets in cancer and neuroscience. He is the author of over 300 papers in scientific journals, with over 45,000 citations. Dr. Wahlestedt is an expert in genomic medicine pertaining to a number of innovative therapeutic modalities and diagnostic approaches.

Claes Wahlestedt,医学博士,SAB主席。迈阿密大学伦纳德·M·米勒医学院治疗创新中心的董事说。Wahlestedt博士在药物发现、基因组学和表观遗传学方面有着长期的学术和大型制药行业的职业生涯,并在这些领域开创了各种翻译工作。从2005年到2011年,瓦赫斯泰特博士是斯克里普斯研究所的教授和董事研究员。在此之前,他在卡罗林斯卡研究所(与Pharmacia/Pfizer的合资企业)创建并运营了基因组学和生物信息学中心。他联合创立的公司包括CuRNA(现在是Opko Health/Camp4的一部分),该公司基于他的专利,以靶向调节性非编码RNA来上调治疗性蛋白质,以及Eigenetix Inc.,专注于针对癌症和神经科学中各种药物靶点的小分子药物。他在科学期刊上发表了300多篇论文,被引用超过45000篇。Wahlestedt博士是基因组医学方面的专家,与许多创新的治疗方式和诊断方法有关。

L. Frank Kolakowski, Ph.D., Senior Scientist, Tetracore, Inc. Dr. Kolakowski has a distinguished 30-year scientific research career that includes positions on the faculty of the University of Texas Health Science Center, as an instructor at Harvard Medical School, and as consultant for several U.S. government agencies. As an entrepreneur, Dr. Kolakowski founded and served as CEO of ReceptorBase from 2000-2004, prior to being hired by the prestigious consulting firm Booz Allen Hamilton to initiate and manage their life sciences practice. He received his Doctorate in Chemistry from the University of Pennsylvania and his B.S. in Biology and Chemistry from Towson State University. Tetracore and Dr. Kolakowski are long term partners of SeqLL.

L.Frank Kolakowski,博士Kolakowski博士拥有30年卓越的科学研究生涯,曾在德克萨斯大学健康科学中心担任教员、哈佛医学院讲师和多个美国政府机构的顾问。作为一名企业家,Kolakowski博士在2000-2004年间创立并担任ReceptorBase的首席执行官,之后受雇于著名的咨询公司Booz Allen Hamilton,启动和管理他们的生命科学业务。他在宾夕法尼亚大学获得化学博士学位,在陶森州立大学获得生物和化学学士学位。Tetracore和Kolakowski博士是SeqLL的长期合作伙伴。

Efrat Shema, Ph.D., Principal Investigator and Assistant Professor at the Weizmann Institute of Science. Recipient of the prestigious Fulbright Scholar, Dr. Shema conducted post-doctoral work under Dr. Bradley Bernstein at Massachusetts General Hospital, Harvard Medical School, and the Broad Institute of MIT and Harvard. During her Ph.D. studies at the Weizmann Institute, Dr. Shema has received multiple prestigious awards, including the Adams Fellowship from the Israel Academy of Sciences and Humanities, the Otto Schwartz Prize for Excellence, and the UNESCO-L'OREAL national award for young women in life sciences. Dr. Shema completed her M.Sc. and Ph.D in molecular cell biology at the Weizmann Institute and earned her B.Sc. in life sciences at the Hebrew University in Jerusalem in 2005.   Dr. Shema's research has focused on using SeqLL's tSMS platform to decode the cancer epigenome since 2014.

Efrat Shema,博士魏茨曼科学研究所首席研究员兼助理教授。谢马博士获得了著名的富布赖特学者奖,在布拉德利·伯恩斯坦博士的指导下,在马萨诸塞州总医院、哈佛医学院以及麻省理工学院和哈佛大学的博士后研究所进行了博士后工作。在魏茨曼研究所攻读博士期间,谢玛博士获得了多个著名奖项,包括以色列科学院和人文学院颁发的亚当斯奖学金、奥托·施瓦茨优秀奖和联合国教科文组织-欧莱雅生命科学领域年轻女性奖。谢马博士完成了她的理学硕士学位。在魏茨曼研究所获得分子细胞生物学博士学位,并获得理科学士学位。2005年在耶路撒冷希伯来大学攻读生命科学专业。自2014年以来,舍马博士的研究重点一直是使用SeqLL的TSMS平台来解码癌症表观基因组。

Timothy McCaffrey, Ph.D., Professor of Medicine and Director, Division of Genomic Medicine, George Washington University. Dr. McCaffrey has had a distinguished career in research focused in three major areas: cardiovascular disease, genomics and stem cells. In 2001, he received a prestigious MERIT award from NIH for his work on vascular aging. Dr. McCaffrey is a close collaborator of ours and has used the tSMS platform to identify several panels of RNA transcripts that are highly predictive biomarkers in the fields of cardiovascular disease, infection and inflammation. He co-founded True Bearing Diagnostics to commercialize diagnostics based on those discoveries. He received post-doctoral training at Cornell University Medical College in New York City, his Masters and Doctorate from Purdue University and his B.A. from St. Mary's University.

蒂莫西·麦卡弗里博士,乔治华盛顿大学基因组医学系医学和董事教授。麦卡弗里博士在心血管疾病、基因组学和干细胞这三个主要领域的研究领域取得了卓越的成就。2001年,他因在血管老化方面的工作而获得美国国立卫生研究院颁发的享有盛誉的功勋奖。McCaffrey博士是我们的密切合作伙伴,他利用TSMS平台识别了几组RNA转录本,这些转录本在心血管疾病、感染和炎症领域具有高度预测性的生物标志物。他与人共同创立了True轴承诊断公司,将基于这些发现的诊断技术商业化。他在纽约市康奈尔大学医学院接受博士后培训,在普渡大学获得硕士和博士学位,在圣玛丽大学获得学士学位。

About True Single Molecule Sequencing (tSMS) Technology
SeqLL's collaborators are thoroughly committed to using only our tSMS platform in their scientific research due to its unique RNA and DNA sequencing and related services. Our true single molecule sequencing platform is NGS technology offers maximum flexibility and avoids many of the challenges common for standard NGS approaches. It that enables direct sequencing of millions of individual molecules not requiring PCR amplification at any stage of the process and a simple, economical sample prep protocols. Therefore, it captures a precise sample composition, without bias and loss of diversity and rare species. Our tSMS platform is ideally suited for RNA biomarker discovery and diagnostic assay developments, including challenging applications for the standard NGS platform, such as low quantity, difficult or degraded samples of cell-free DNA, FFPE-isolated nucleic acids, ancient DNA and forensic samples.

关于真单分子测序(TSMS)技术
SeqLL的合作者完全致力于在他们的科学研究中只使用我们的TSMS平台,因为它具有独特的RNA和DNA测序及相关服务。我们真正的单分子测序平台是NGS技术,提供了最大的灵活性,避免了标准NGS方法常见的许多挑战。它使数百万个单独的分子能够直接测序,而不需要在过程的任何阶段进行PCR扩增,以及简单、经济的样品制备方案。因此,它捕获了准确的样品组成,没有偏见,没有多样性和稀有物种的损失。我们的TSMS平台非常适合于RNA生物标记物的发现和诊断分析开发,包括标准NGS平台的挑战性应用,例如低数量、困难或降解的无细胞DNA样本、FFPE分离的核酸、古代DNA和法医样本。

About SeqLL, Inc.
SeqLL Inc. ("SeqLL") is a technology company providing life sciences instrumentation and research services in collaborative partnerships aimed at the development of novel scientific assets and intellectual property across multiple "omics" fields. The Company leverages its expertise with its True Single Molecule Sequencing ("tSMS®") platform to empower scientists and researchers with improved genetic tools to better understand the molecular mechanisms of disease that is essential to the continued development of new breakthroughs in genomic medicine, and that hopefully address the critical concerns involved with today's precision medicine. In sum, our experienced team works with our collaborators to develop innovative solutions tailored to the needs of each specific project.

SeqLL公司简介
SeqLL Inc.(“SeqLL”)是一家以合作伙伴关系提供生命科学仪器和研究服务的技术公司,旨在跨多个“组学”领域开发新的科学资产和知识产权。该公司利用其真正的单分子测序(“TSMS®”)平台的专业知识,为科学家和研究人员提供改进的基因工具,使他们能够更好地了解疾病的分子机制,这对继续发展基因组医学的新突破至关重要,并有望解决与当今精确医学相关的关键问题。总而言之,我们经验丰富的团队与我们的合作者一起开发针对每个特定项目的需求而量身定做的创新解决方案。

Forward Looking Statements
This press release contains certain forward-looking statements, including those related to the applicability and viability of the Company's technology to quantifying RNA molecules from blood and other statements that are predictive in nature. Forward-looking statements are based on the Company's current expectations and assumptions. The Private Securities Litigation Reform Act of 1995 provides a safe-harbor for forward-looking statements. These statements may be identified by the use of forward-looking expressions, including, but not limited to, "expect," "anticipate," "intend," "plan," "believe," "estimate," "potential," "predict," "project," "should," "would" and similar expressions and the negatives of those terms. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this presentation. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in the Company's filings with the Securities and Exchange Commission, including its registration statement on Form S-1, as amended, under the caption "Risk Factors."

前瞻性陈述
本新闻稿包含某些前瞻性陈述,包括与该公司量化血液中RNA分子的技术的适用性和可行性有关的陈述,以及其他具有预测性的陈述。前瞻性陈述是基于公司目前的预期和假设。1995年的《私人证券诉讼改革法》为前瞻性陈述提供了避风港。这些表述可以通过使用前瞻性表述来识别,包括但不限于“预期”、“预期”、“打算”、“计划”、“相信”、“估计”、“潜在”、“预测”、“项目”、“应该”、“将”以及类似的表述和这些术语的否定。告诫潜在投资者不要过度依赖此类前瞻性陈述,这些陈述仅在本报告发表之日发表。公司不承担公开更新任何前瞻性陈述的义务,无论是由于新信息、未来事件还是其他原因。可能导致实际结果与前瞻性陈述大不相同的重要因素在该公司提交给证券交易委员会的文件中陈述,包括其在“风险因素”标题下的S-1表格注册陈述。

Contacts:

联系人:

Ashley R. Robinson
LifeSci Advisors, LLC
Tel: +1 (617) 430-7577
Email: arr@lifesciadvisors.com

阿什利·R·罗宾逊
生活科学顾问有限责任公司
电话:+1(617)430-7577
电子邮件:arr@lifescivisors.com


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