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Takeda Inks $2B Gene Therapy Pact With Code Biotherapeutics

Takeda Inks $2B Gene Therapy Pact With Code Biotherapeutics

武田與Code BioTreatetics簽署價值20億美元的基因治療協議
Benzinga Real-time News ·  2022/02/22 12:46

Takeda Pharmaceutical Co Ltd (NYSE:TAK) has signed up for a gene therapy pact, encoding a $2 billion biobucks deal with Code Biotherapeutics across four programs.

武田藥業株式會社(紐約證券交易所股票代碼:TAK)已經簽署了一項基因治療協議,編碼了一項價值20億美元的生物垃圾交易密碼生物治療學橫跨四個項目。

  • The collaboration entails deploying Code's non-viral gene therapies against liver-directed rare disease and central nervous system conditions. 
  • Through the agreement, Takeda and Code Bio will design and develop a targeted gene therapy leveraging Code Bio's 3DNA platform for a liver-directed rare disease program.
  • The companies will conduct additional studies for central nervous system-directed rare disease programs. 
  • Takeda has the right to exercise options for an exclusive license for four programs. 
  • Under the agreement terms, Code Bio will receive double-digit million dollars in upfront, near-term milestones, and research funding payments. 
  • Code Bio is also eligible to receive future development and commercial milestone payments plus tiered royalties with a potential total deal value of up to $2 billion if milestones for all four programs are achieved. 
  • Takeda and Code Bio will collaborate on research activities up to candidate selection. After the option exercise, Takeda will assume responsibility for further development and commercialization.
  • Price Action: TAK shares are down 1.89% at $15.06 during the market session on the last check Tuesday.
  • 這項合作需要部署Code的非病毒基因療法,以對抗肝臟相關的罕見疾病和中樞神經系統疾病。
  • 通過這項協議,武田和Code Bio將利用Code Bio的3DNA平臺設計和開發一種有針對性的基因療法,用於肝臟導向的罕見疾病計劃。
  • 這兩家公司將對中樞神經系統指導的罕見疾病項目進行額外的研究。
  • 武田有權行使四個項目獨家許可的選擇權。
  • 根據協議條款,Code Bio將獲得兩位數的百萬美元預付款、近期里程碑和研究資金。
  • 代碼生物公司還有資格獲得未來開發和商業里程碑付款以及分級特許權使用費,如果所有四個項目都達到里程碑,潛在交易總價值將高達20億美元。
  • 武田和Code Bio將在候選人選擇之前的研究活動中進行合作。選擇權行使後,武田將承擔進一步開發和商業化的責任。
  • 價格行動:週二尾盤,德意志銀行股價下跌1.89%,至15.06美元。
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