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Rani Therapeutics to Present Clinical and Preclinical Data on Oral Delivery of an Ustekinumab Biosimilar via the RaniPill Capsule at Digestive Disease Week 2024

Rani Therapeutics to Present Clinical and Preclinical Data on Oral Delivery of an Ustekinumab Biosimilar via the RaniPill Capsule at Digestive Disease Week 2024

Rani Therapeutics将在2024年消化系统疾病周上公布通过RaniPill胶囊口服Ustekinumab生物仿制药的临床和临床前数据
GlobeNewswire ·  05/09 08:00

SAN JOSE, Calif., May 09, 2024 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. ("Rani Therapeutics" or "Rani") (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral delivery of biologics and drugs, today announced that it will present clinical and preclinical and data on the RaniPill capsule, the company's oral delivery platform, at Digestive Disease Week (DDW) taking place both virtually and in-person on May 18-21, 2024 in Washington, DC.

加利福尼亚州圣何塞,2024年5月9日(GLOBE NEWSWIRE)——专注于生物制剂和药物口服给药的临床阶段生物治疗公司Rani Therapeutics Holdings, Inc.(“Rani Therapeutics” 或 “Rani”)(纳斯达克股票代码:Rani)今天宣布,它将提供有关RaniPill的临床和临床前以及数据 该公司的口服给药平台胶囊在消化疾病周上亮相 (DDW) 将于 2024 年 5 月 18 日至 21 日在华盛顿特区以虚拟方式和面对面形式举行。

Details of the presentations are as follows:

演讲详情如下:

Abstract Title: An Orally Administered Robotic Pill (RP) Reliably and Safely Delivers an Ustekinumab Biosimilar RT-111 with High Bioavailability Relative to Subcutaneous (SC) Ustekinumab in Healthy Human Participants
Session Type: Late-Breaking Oral Presentation
Session Title: IMIBD Late Breakers and Innovations in IBD
Session Date & Time: May 19, 2024 from 2:00 – 3:30 EDT
Presentation Time: 3:00 PM to 3:15 PM EDT
Session Number: 3465
Presenting Author: Jacques Van Dam, MD, PhD

摘要标题:与皮下(SC)Ustekinumab相比,一种口服给药的机器人药丸(RP)可靠、安全地在健康人体参与者中提供具有高生物利用度的Ustekinumab生物仿制药 RT-111
会议类型:最新口头演讲
会议标题:IMIBD IBD 的 LateBreakers 和 IBD 创新
会议日期和时间:美国东部时间 2024 年 5 月 19 日 2:00 — 3:30
演示时间:美国东部时间下午 3:00 至下午 3:15
会话编号:3465
主讲作者:雅克·范丹,医学博士,博士

Abstract Title: Orally-Administered Ustekinumab Biosimilar RT-111 Delivered Via a Robotic Pill Yields Bioavailability Comparable to Subcutaneous Injection in Canines
Session Type: Poster Session
Session Title: Animal Models of IBD: Pre-Clinical Treatment of Intestinal Inflammation
Session Date & Time: May 21, 2024 from 12:30 PM to 1:30 PM EDT
Poster No: Tu1729
Presenting Author: Kyle Horlen, DVM

摘要标题:通过机器人药丸口服的 Ustekinumab 生物仿制药 RT-111 的生物利用度可与犬类皮下注射相媲美
会议类型:海报会议
会议标题:IBD 动物模型:肠道炎症的临床前治疗
会议日期和时间:2024 年 5 月 21 日美国东部时间下午 12:30 至下午 1:30
海报编号:Tu1729
主讲作者:凯尔·霍伦,DVM

Abstracts selected by the American Gastroenterological Association (AGA) for presentation at DDW will be available in a supplement to Gastroenterology. The presentations and information about DDW 2024 may be accessed at

美国胃肠病学协会(AGA)精选的在DDW上发表的摘要将作为补编提供 胃肠病学。有关 DDW 2024 的演示和信息可在以下网址获取

About Digestive Disease Week

关于消化系统疾病周

Digestive Disease Week (DDW) is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA), the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT), DDW is an in-person and online meeting from May 18-21, 2024. The meeting showcases more than 4,400 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. More information can be found at .

消化系统疾病周 (DDW) 是胃肠病学、肝病学、内窥镜检查和胃肠道外科领域最大的医生、研究人员和学者国际聚会。DDW由美国肝脏疾病研究协会(AASLD)、美国胃肠病学会(AGA)、美国胃肠道内窥镜学会(ASGE)和消化道外科学会(SSAT)共同赞助,是一次面对面的在线会议,将于2024年5月18日至21日举行。会议展示了有关胃肠道研究、医学和技术最新进展的4,400多份摘要和数百场讲座。更多信息可以在以下网址找到。

About RaniPill Capsule

关于 RaniPill 胶囊

Rani Therapeutics has developed a disruptive technology for the oral delivery of biologics. The RaniPill Capsule is an innovative robotic pill that moves fully intact through the stomach, where acids typically break down drugs, and then reaches the intestine, where it delivers the drug via transenteric injection. The injection is painless, and the drug is rapidly absorbed.

Rani Therapeutics开发了一种用于口服生物制剂的颠覆性技术。RaniPill 胶囊是一种创新的机器人药丸,它能完好无损地穿过胃部,酸通常在胃中分解药物,然后到达肠道,在那里通过经肠道注射输送药物。注射无痛,药物可迅速吸收。

About RT-111

关于 RT-111

RT-111 is an orally administered RaniPill capsule containing an ustekinumab biosimilar, CT-P43, designed to offer a highly differentiated dosing regimen for patients with psoriasis and other chronic inflammatory diseases compared to both injectable biologics and oral small molecules and peptides.

RT-111 是一种口服的 RaniPill 含有ustekinumab生物仿制药 CT-P43 的胶囊,与可注射生物制剂和口服小分子和肽相比,该胶囊旨在为牛皮癣和其他慢性炎症性疾病患者提供高度差异化的给药方案。

About Rani Therapeutics

关于拉尼疗法

Rani Therapeutics is a clinical stage biotherapeutics company focused on advancing technologies to enable the development of orally administered biologics and drugs. Rani has developed the RaniPill capsule, which is a novel, proprietary and patented platform technology, intended to replace subcutaneous injection or intravenous infusion of biologics and drugs with oral dosing. Rani has successfully conducted several preclinical and clinical studies to evaluate safety, tolerability and bioavailability using RaniPill capsule technology. For more information, visit ranitherapeutics.com.

Rani Therapeutics是一家临床阶段的生物治疗公司,致力于推进技术进步,实现口服生物制剂和药物的开发。Rani 开发了 RaniPill 胶囊是一种新颖的专有专利平台技术,旨在用口服剂量取代生物制剂和药物的皮下注射或静脉输注。Rani已成功进行了多项临床前和临床研究,以评估使用RaniPill的安全性、耐受性和生物利用度 胶囊技术。欲了解更多信息,请访问ranitherapeutics.com。

Investor Contact:

投资者联系人:

investors@ranitherapeutics.com

investors@ranitherapeutics.com

Media Contact:

媒体联系人:

media@ranitherapeutics.com

media@ranitherapeutics.com


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