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Enzolytics, Inc. Announces Execution of Non-Binding Term Sheet With the Special Purpose Acquisition Company Sagaliam Acquisition Corp. and Updates the Progress on the African Project

Enzolytics, Inc. Announces Execution of Non-Binding Term Sheet With the Special Purpose Acquisition Company Sagaliam Acquisition Corp. and Updates the Progress on the African Project

Enzolytics, Inc. 宣布与特殊目的收购公司Sagaliam Acquisition Corp. 执行不具约束力的条款表,并更新了非洲项目的进展情况
Accesswire ·  2023/04/17 07:07

COLLEGE STATION, TX / ACCESSWIRE / April 17, 2023 / Enzolytics, Inc. (OTC PINK:ENZC) (

德克萨斯州大学城/Accesswire/2023 年 4 月 17 日/ Enzolytics, Inc.(OTC PINK: ENZC)(

Enzolytics, Inc. (the "Company" or "ENZC"), a drug development biotech company, and Sagaliam Acquisition Corp. (NASDAQ: SAGA) ("Sagaliam"), a special purpose acquisition company ("SPAC"), announced today, April 17, 2023, they have executed a non-binding term sheet for the sale of Biogenysis, Inc. ("BGEN") and Virogentics, Inc. ("VIRO"), operating subsidiaries of Enzolytics. The value of the transaction is $250,000,000 The definitive agreement is being finalized with an expected closing date of May 19, 2023.

药物开发生物技术公司Enzolytics, Inc.(“公司” 或 “ENZC”)和特殊目的收购公司(“SPAC”)Sagaliam Acquisition Corp.(“Sagaliam”)今天,即2023年4月17日宣布,他们已经执行了出售Biogenysis, Inc.(“BGEN”)和Virogentics的不具约束力的条款表,Inc.(“VIRO”),Enzolytics的运营子公司。该交易的价值为2.5亿美元最终协议正在敲定中,预计截止日期为2023年5月19日。

Under the terms of the agreement, BGEN and VIRO will become wholly owned subsidiaries of Sagaliam, currently trading on NASDAQ, and will adopt SAGA Scientific Holdings Corp. as the corporate name.

根据协议条款,BGEN和VIRO将成为Sagaliam的全资子公司,目前在纳斯达克上市,并将采用SAGA Scientific Holdings Corp. 作为公司名称。

The transaction, once completed, will provide BGEN and VIRO with significant additional capital to continue their development and expansion of existing and future technology platforms. In addition, Sagaliam expects to raise additional capital through a private investment in public equities ("PIPE"). The anticipated capital raise from the PIPE is expected to be primarily used by BGEN and VIRO to pay transaction-related expenses and fund the clinical trials of ITV-1, marketing of IPF Immune, production of fully human monoclonal antibodies (mAbs) and continued advancement in its proprietary technology involving the application of Artificial Intelligence (AI) in therapeutic discoveries and production.

该交易一旦完成,将为BGEN和VIRO提供大量额外资金,以继续开发和扩展现有和未来的技术平台。此外,萨加拉姆预计将通过私人投资公募股权(“PIPE”)筹集更多资金。预计PIPE筹集的资金将主要由BGEN和VIRO用于支付交易相关费用和资助 ITV-1 的临床试验、IPF Immune 的营销、全人源单克隆抗体(mAB)的生产以及其涉及在治疗发现和生产中应用人工智能(AI)的专有技术的持续发展。

The Chief Scientific Officer of VIRO, Harry Zhabilov, offered the following update on the production of ITV-1 vials for the Africa initiative and European Medicines Agency ("EMA") permitting progress, "Production of the necessary anti-HIV immunotherapy treatments for use in the hospitals located in Central and Eastern regions of Africa was successfully completed on April 12, 2023, and will be delivered to the hospitals in the coming weeks." With the preliminary results of Toxicology studies of the Company's ITV-1 anti-HIV therapeutic confirming that the therapy is non-toxic and demonstrating the safety of administration of this patented proprietary immunotherapy, VIRO has negotiating a contract with a German company to perform the pharmacokinetics methodology the EMA has required as part of the EMA permitting process. VIRO wishes to recognize the contribution that Dr. Lachezar Ivanov has made in this endeavor."

VIRO 首席科学官哈里·扎比洛夫提供了以下关于为非洲倡议和欧洲药品管理局(“EMA”)生产 ITV-1 小瓶的最新情况,允许取得进展,“供非洲中部和东部地区医院使用的必要抗艾滋病毒免疫疗法疗法的生产已于 2023 年 4 月 12 日成功完成,并将在未来几周内交付给医院。”该公司 ITV-1 抗 HIV 疗法的毒理学研究的初步结果证实了该疗法是无毒的,并证明了这种专利专有免疫疗法的给药安全性,VIRO 正在与一家德国公司谈判一份合同,以执行 EMA 要求的药代动力学方法,这是EMA许可程序的一部分。VIRO 希望表彰博士的贡献拉切扎尔·伊万诺夫在这项努力中做出了努力。”

The CEO of BGEN, Dr. Gaurav Chandra, emphasized the progress being made by the Company using its Artificial Intelligence (AI) platform. "We continue to utilize our disruptive AI platform to identify conserved immutable epitopes on viruses and then produce species-specific monoclonal antibodies targeting those sites. We are advancing in production of multiple monoclonal antibodies against HIV, SARS-CoV-2, and the Feline Leukemia virus. Our AI platform drives the Company's drug discovery and development and executes our strategy to produce multiple therapeutics protected by International Patents. We take pride in strengthening our IP portfolio and protecting the anti-virus therapeutics, their production method, use in diagnostics and prognostics. Our application of Artificial Intelligence to drug formulation and creation is a move ahead of big pharma's monoclonal antibody discovery and development. We recognize that large pharmaceutical companies are now focused more than ever on the significant advantage provided by AI in creating highly successful therapeutics. We continue to engage with large pharma and discuss potential partnerships involving our AI platform."

BGEN首席执行官高拉夫·钱德拉博士强调了公司利用其人工智能(AI)平台取得的进展。“我们将继续利用我们的颠覆性人工智能平台来识别病毒上保存的不可变表位,然后生产针对这些位点的物种特异性单克隆抗体。我们在针对HIV、SARS-CoV-2和猫白血病病毒的多种单克隆抗体的生产方面正在取得进展。我们的人工智能平台推动了公司的药物发现和开发,并执行了我们生产受国际专利保护的多种疗法的战略。我们为加强我们的知识产权组合、保护抗病毒疗法、其生产方法、在诊断和预测中的用途而感到自豪。我们将人工智能应用于药物配方和创造,是大型制药公司在单克隆抗体发现和开发方面向前迈出的一步。我们认识到,大型制药公司现在比以往任何时候都更加关注人工智能在创造非常成功的疗法方面提供的巨大优势。我们将继续与大型制药公司接触,并讨论涉及我们的人工智能平台的潜在合作伙伴关系。”

Enzolytics CEO Charles Cotropia stated, "Enzolytics is focused on accelerating the growth of our clinical products, technology platforms and multiple programs now in progress. This agreement with Sagaliam will allow us to accelerate progress in each of these areas."

Enzolytics首席执行官查尔斯·科特罗皮亚表示:“Enzolytics专注于加速我们目前正在进行的临床产品、技术平台和多个项目的增长。与萨加拉姆的这项协议将使我们能够加快这些领域的进展。”

Enzolytics, Inc. Overview

Enzolytics, Inc. 概述

Enzolytics, Inc. is a drug development company committed to commercializing its proprietary proteins and monoclonal antibodies to treat debilitating infectious diseases. The Company is advancing multiple therapeutics targeting numerous infectious diseases. One patented and clinically tested compound, ITV-1 (Immune Therapeutic Vaccine-1), is a suspension of Inactivated Pepsin Fraction (IPF), covered by U.S. Patent Nos. 8,066,982 and 7,479,538. Studies have shown it to be effective in treating HIV/AIDS. ITV-1 has also been shown to modulate the immune system.

Enzolytics, Inc. 是一家药物开发公司,致力于将其专有蛋白质和单克隆抗体商业化,以治疗使人衰弱的传染病。该公司正在推进针对多种传染病的多种疗法。一种获得专利并经过临床测试的化合物 ITV-1(免疫治疗疫苗-1)是灭活胃蛋白酶组分(IPF)的悬浮液,受美国专利号 8,066,982 和 7,479,538 的保护。研究表明,它可以有效治疗艾滋病毒/艾滋病。ITV-1 也被证明可以调节免疫系统。

The Company has proprietary technology for producing fully human monoclonal antibodies (mAbs) against infectious diseases which are currently being employed to produce monoclonal antibody therapeutics for treating the CoronaVirus (SARS-CoV-2), HIV-1 and the Feline Leukemia virus. The Company has also identified conserved epitopes on and has plans to produce mAbs targeting many other viruses, including HIV-2, Influenza A and B, H1N1 influenza, Respiratory syncytial virus (RSV), Small-Pox, Ebola Virus, Tetanus, Diphtheria, HTLV-1/2, Rabies, Herpes zoster, Varicella zoster, Anthrax, Mason-Pfizer monkey virus (MPMV) and Visna virus (VISNA). The Company has also analyzed epitopes of animal viruses and plans to produce mAbs for treating these animal viruses.

该公司拥有生产针对传染病的全人单克隆抗体(mAB)的专有技术,这些单克隆抗体目前正用于生产用于治疗冠状病毒(SARS-CoV-2)、HIV-1 和猫白血病病毒的单克隆抗体疗法。该公司还发现了针对许多其他病毒的保存表位,并计划生产针对许多其他病毒的单克隆抗体,包括 HIV-2、甲型和乙型流感、H1N1 流感、呼吸道合胞病毒 (RSV)、小痘、埃博拉病毒、破伤风、白喉、HTLV-1/2、狂犬病、带状疱疹、水痘带状疱疹、炭疽病毒、梅森-辉瑞猴病毒 (MPMV))和维斯纳病毒(VISNA)。该公司还分析了动物病毒的表位,并计划生产用于治疗这些动物病毒的单抗体。

Sagaliam Overview

萨加拉姆概述

Sagaliam is a SPAC that raised $116.5 million in its initial public offering on December 23, 2021. The current available cash after redemptions is approximately $10 million.

萨加里亚姆是一家特殊目的收购公司,在2021年12月23日的首次公开募股中筹集了1.165亿美元。赎回后的当前可用现金约为1000万美元。

The purchase agreement between ENZC and Sagaliam requires that the sponsor agree not to sell its founder shares for a period of six months after the business combination subject to the provisions of the lock-up agreement. The sponsor believes that this "lock-up" period aligns the interests of the sponsor with those of Sagaliam's investors. As such, with certain limited exceptions, the sponsor expects to continue to be invested in the combined company after the completion of the purchase agreement.

ENZC和Sagaliam之间的收购协议要求赞助商同意在业务合并后的六个月内不出售其创始人股份,但须遵守封锁协议的规定。保荐人认为,这个 “封锁” 期使保荐人的利益与萨加利亚姆投资者的利益一致。因此,除某些有限的例外情况外,保荐人预计在收购协议完成后将继续投资合并后的公司。

Safe Harbor Statement: This news release contains forward-looking statements that involve risks and uncertainties associated with financial projections, budgets, milestone timelines, clinical development, regulatory approvals, and other risks described by Enzolytics, Inc. from time to time in its periodic reports filed with the SEC. ITV-1 is not approved by the U.S. Food and Drug Administration or by any comparable regulatory agencies elsewhere in the world.

安全港声明:本新闻稿包含前瞻性陈述,涉及与财务预测、预算、里程碑时间表、临床开发、监管批准以及Enzolytics, Inc.在向美国证券交易委员会提交的定期报告中不时描述的其他风险相关的风险和不确定性。ITV-1 未获得美国食品药品监督管理局或世界其他地方任何类似监管机构的批准。

While Enzolytics, Inc. believes that the forward-looking statements and underlying assumptions contained therein are reasonable, any of the assumptions could be inaccurate, including, but not limited to, the ability of Enzolytics to establish the efficacy of its therapeutics in the treatment of any disease or health condition, the development of studies and strategies leading to commercialization of its therapeutics in the United States, the obtaining of funding required to carry out the development plan, the completion of studies and tests on time or at all, and the successful outcome of such studies or tests. Therefore, there can be no assurance that the forward-looking statements included in this release will prove to be accurate.

尽管 Enzolytics, Inc. 认为其中包含的前瞻性陈述和基本假设是合理的,但任何假设都可能不准确,包括但不限于Enzolytics确定其疗法在治疗任何疾病或健康状况方面的疗效的能力、制定导致其疗法在美国商业化的研究和战略、获得执行开发计划所需的资金、完成研究以及准时或完全进行测试,以及此类研究或测试的成功结果。因此,无法保证本新闻稿中包含的前瞻性陈述会被证明是准确的。

Such forward-looking statements are based on current expectations. They involve inherent risks and uncertainties, including factors that could delay, divert or change any of the statements made, and cause actual outcomes and results to differ materially from current expectations. No forward-looking statement can be guaranteed. These forward-looking statements are made as of the date of this press release. The Company expressly disclaims any intention or obligation to update the forward-looking statements or update the reasons why actual results could differ from those projected in the forward-looking statements.

此类前瞻性陈述基于当前的预期。它们涉及固有的风险和不确定性,包括可能延迟、转移或改变任何陈述的因素,并导致实际结果和结果与当前预期存在重大差异。无法保证任何前瞻性陈述。这些前瞻性陈述截至本新闻稿发布之日作出。公司明确表示无意或无义务更新前瞻性陈述或更新实际业绩可能与前瞻性陈述中预测的结果不同的理由。

Company Contact:

公司联系人:

Enzolytics, Inc.
1101 Raintree Circle
Allen, Texas 75013

Enzolytics, Inc.
1101 雨树圈
得克萨斯州艾伦 75013

SOURCE: Enzolytics, Inc.

来源: Enzolytics, Inc.


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