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EXCLUSIVE: Takeda's Cancer Partner BridGene Raises $38.5M To Accelerate Work On Undruggable Targets

EXCLUSIVE: Takeda's Cancer Partner BridGene Raises $38.5M To Accelerate Work On Undruggable Targets

独家报道:武田的癌症合作伙伴Bridgene筹集了3850万美元,以加快研发无法用药的靶点
Benzinga Real-time News ·  2022/07/27 06:46

BridGene Biosciences Inc has completed a $38.5 million Series B financing by Lapam Capital, Junson Capital, and Dyee Capital.

Bridgene生物科学公司已经完成了由Lapam Capital、Junson Capital和Dyee Capital进行的3850万美元的B系列融资。

The platform enables screening small molecules against the whole proteome or a prioritized target in live cells to discover drug candidates for undruggable targets, including cancers.

该平台能够针对整个蛋白质组或活细胞中的优先靶点筛选小分子,以发现不可用药的候选药物目标,包括癌症。

BridGene's IMTAC can identify hits for targets with shallow binding pockets. BridGene can also identify hits via live cell screening for targets with temporary binding pockets that only form in live cells, such as protein.

Bridgene的IMTAC可以识别绑定口袋较浅的目标。Bridgene还可以通过活细胞筛选具有仅在活细胞中形成的临时结合口袋的靶点来识别命中,例如蛋白质。

Why It Is Important: The company will use the proceeds to develop its chemoproteomic platform IMTAC.

为什么它很重要:该公司将利用所得资金开发其化学蛋白质组平台IMTAC。

The money will also be used to develop BridGene's leading pipeline project, a covalent TEAD inhibitor, and a few other undisclosed oncology pipeline projects based on the IMTAC platform.

这笔资金还将用于开发Bridgene的领先管道项目,一种共价Tead抑制剂,以及基于IMTAC平台的其他几个未披露的肿瘤学管道项目。

Last year, the company announced a research collaboration and licensing agreement with Takeda Pharmaceutical Company Limited (NYSE:TAK).

去年,该公司宣布与以下公司达成研究合作和许可协议武田药品株式会社(纽约证券交易所股票代码:Tak)。

The companies will establish up to five drug discovery programs, harnessing BridGene's proprietary IMTAC. Takeda will develop the therapeutic candidates and pursue clinical development. 

两家公司将建立最多五个药物发现计划,利用Bridgene的专利IMTAC。武田将开发治疗候选药物,并致力于临床开发。

BridGene is eligible to receive potential milestone payments over $500 million and sales-based royalties.

Bridgene有资格获得超过5亿美元的潜在里程碑付款和基于销售的特许权使用费。

Price Action: TAK shares closed at $14.55 on Tuesday.

价格行动:周二,德意志银行的股价收于14.55美元。

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