Following the market opening Wednesday, the Dow traded down 0.30% to 35,706.59 while the NASDAQ fell 0.61% to 15,678.70. The S&P also fell, dropping 0.34% to 4,674.85.

Leading and Lagging Sectors

Energy shares gained by 1.5% on Wednesday. Meanwhile, top gainers in the sector included $Altus Midstream(ALTM.US)$, up 5%, and $Amplify Energy(AMPY.US)$ up 5%.

In trading on Wednesday, information technology shares fell 0.6%.

Top Headline

$Deere(DE.US)$ reported upbeat results for its fourth quarter on Wednesday.

Deere posted quarterly earnings of $4.12 per share, beating analysts’ estimates of $3.90 per share. The company’s quarterly sales came in at $11.33 billion, versus expectations of $10.44 billion.

Deere said it sees FY22 net income of $6.5 billion to $7 billion.

Equities Trading UP

$Biofrontera(BFRI.US)$ shares shot up 115% to $5.66 after Roth Capital initiated coverage on the stock with a Buy rating and a $20 price target.

Shares of $Longeveron(LGVN.US)$ got a boost, shooting 50% to $25.82 after tumbling 39% on Tuesday. The company last week announced the FDA granted Rare Pediatric Disease designation for Lomecel-B for the treatment of Hypoplastic Left Heart Syndrome.

$Better Therapeutics(BTTX.US)$ shares were also up, gaining 41% to $9.13 after Chardan Capital initiated coverage on the stock with a Buy rating and a $17 price target.

Equities Trading DOWN

$Qualigen Therapeutics(QLGN.US)$ shares tumbled 36% to $1.64 after jumping around 105% on Tuesday.

Shares of $Vallon Pharmaceuticals(VLON.US)$ were down 31% to $5.01 after jumping over 80% on Tuesday.

$Petros Pharmaceuticals(PTPI.US)$ was down, falling 29% to $1.6499 after jumping over 75% on Tuesday.

Commodities

In commodity news, oil traded down 0.5% to $78.11, while gold traded up 0.3% to $1,789.50.

Silver traded up 0.6% Wednesday to $23.575 while copper rose 0.7% to $4.4555.

Euro zone

European shares were lower today. The eurozone’s STOXX 600 fell 0.1%, the Spanish Ibex Index fell 0.2% and the German DAX 30 dropped 0.6%. Meanwhile, the London's FTSE 100 fell 0.1%, French CAC 40 fell 0.5% and Italy’s FTSE MIB slipped 0.1%.

The Ifo Business Climate indicator for Germany dropped for the fifth month to 96.5 in November, while the manufacturing climate indicator in France climbed to 109 in November from 107.

Economics

US durable goods orders dropped 0.5% month-over-month in October.

The US economy grew by an annualized rate of 2.1% on quarter in the third qaurter.

The US goods trade deficit shrank to $82.9 billion in October from $97 billion trade gap in September.

US initial jobless claims fell to 199,000 in the week ending November 20th, versus a revised level of 270,000 in the prior period.

Wholesale inventories climbed 2.2% to $758.5 billion in October.

New home sales rose 0.4% to an annual rate of 745,000 in October.

US personal spending rose 1.3% in October, while personal income rose 0.5%.

The University of Michigan's consumer sentiment index was revised higher to 67.4 in November from a preliminary reading of 66.8.

The Energy Information Administration’s weekly report on petroleum inventories in the U.S. is scheduled for release at 10:30 a.m. ET.

The survey of business uncertainty for November will be released at 11:00 a.m. ET.

The EIA’s weekly report on natural gas stocks in underground storage is scheduled for release at 12:00 p.m. ET.

The Baker Hughes North American rig count report for the latest week will be released at 1:00 p.m. ET.

The Federal Open Market Committee will issue minutes of its latest meeting at 2:00 p.m. ET.