$Avalo Therapeutics(AVTX.US$ stock is rocketing higher on Thursday after announcing a couple of positive updates for investors in the clinical-stage biotechnology company.
The first big update worth noting is the company securing $185 million through a private placement. This funding comes from an agreement with institutional investors.
The private placement includes $115.6 million of non-voting convertible preferred stock and warrants worth another $69.4 million...
The first big update worth noting is the company securing $185 million through a private placement. This funding comes from an agreement with institutional investors.
The private placement includes $115.6 million of non-voting convertible preferred stock and warrants worth another $69.4 million...
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Several highly anticipated PDUFA decisions are approaching..👇
Abeona Therapeutics ($Abeona Therapeutics(ABEO.US$ )
Asset: Pz-cel (prademagene zamikeracel)
PDUFA Date: May 25, 2024
Indication: Recessive dystrophic epidermolysis bullosa (RDEB)
Technology: Autologous cell therapy, treatment uses gene transfer to deliver COL7A1 genes into an RDEB patient’s own skin cells then transplanting them back to the patient.
Rocket Pharmaceuticals ($Rocket Pharmaceuticals(RCKT.US$ ) ...
Abeona Therapeutics ($Abeona Therapeutics(ABEO.US$ )
Asset: Pz-cel (prademagene zamikeracel)
PDUFA Date: May 25, 2024
Indication: Recessive dystrophic epidermolysis bullosa (RDEB)
Technology: Autologous cell therapy, treatment uses gene transfer to deliver COL7A1 genes into an RDEB patient’s own skin cells then transplanting them back to the patient.
Rocket Pharmaceuticals ($Rocket Pharmaceuticals(RCKT.US$ ) ...
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$Merck & Co(MRK.US$ FDA Approves WINREVAIR™ (sotatercept-csrk) 🥳
🥇 First-in-class Tx for adults with pulmonary arterial hypertension (PAH WHO Group 1)
📌 significantly improved exercise capacity & multiple important secondary outcome measures
ℹ️ WINREVAIR™
⇒ injection for SC use 💉
⇒ previously granted Breakthrough Therapy Designation
⇒ BLA w/ assigned PDUFA 3/26/24
🥇 First-in-class Tx for adults with pulmonary arterial hypertension (PAH WHO Group 1)
📌 significantly improved exercise capacity & multiple important secondary outcome measures
ℹ️ WINREVAIR™
⇒ injection for SC use 💉
⇒ previously granted Breakthrough Therapy Designation
⇒ BLA w/ assigned PDUFA 3/26/24
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$AstraZeneca(AZN.US$ Ultomiris now approved for Tx of
neuromyelitis optica spectrum disorder (NMOSD)
⇒ sBLA approved as 4th indication 👏
⇒ 1st and only long-acting C5 complement inhibitor,
offers Px with AQP4 Ab+
⇒ CHAMPION-NMOSD trial - met primary endpoint 🔬
⇒ Ultomiris (ravulizumab-cwvz) inj., for IV use 💉
neuromyelitis optica spectrum disorder (NMOSD)
⇒ sBLA approved as 4th indication 👏
⇒ 1st and only long-acting C5 complement inhibitor,
offers Px with AQP4 Ab+
⇒ CHAMPION-NMOSD trial - met primary endpoint 🔬
⇒ Ultomiris (ravulizumab-cwvz) inj., for IV use 💉
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20 public and private funding events 👇
– Private Funding –
Clasp Therapeutics
🏦 Launched w/ $150M Series A financing from several investors to develop their T-cell engagers (TCE) pipeline.
Capstan Therapeutics
🏦 Closed $175M Series B financing led by RA Capital Management to support the advancement of CPTX2309, their in vivo CAR-T product candidate.
Engrail Therapeutics
🏦 Closed $157M Series B financing round to advance the development of their therapies.
Pan...
– Private Funding –
Clasp Therapeutics
🏦 Launched w/ $150M Series A financing from several investors to develop their T-cell engagers (TCE) pipeline.
Capstan Therapeutics
🏦 Closed $175M Series B financing led by RA Capital Management to support the advancement of CPTX2309, their in vivo CAR-T product candidate.
Engrail Therapeutics
🏦 Closed $157M Series B financing round to advance the development of their therapies.
Pan...
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🗓️ Last week’s PDUFAs:
$Orchard Therapeutics(ORTX.US$ (Kyowa Kirin): Approved 🎉
⇒ Lenmeldy (atidarsagene autotemcel)
⇒ early-onset MLD
⇒ BLA
⇒ PDUFA: 3/18/24
$Esperion Therapeutics(ESPR.US$ : Approved 🎉
⇒ Nexletol (bempedoic acid) & Nexlizet (bempedoic acid and ezetimibe)
⇒ CV risk reduction, primary hyperlipidemia (HeFH)
⇒ sNDA
⇒ PDUFA: 3/31/24
📌 This week’s PDUFAs:
$Merck & Co(MRK.US$ : 🤔
⇒ Sotatercept
⇒ Pulmonary arterial hypertension
⇒ BLA
⇒ PDUFA: 3/26/24...
$Orchard Therapeutics(ORTX.US$ (Kyowa Kirin): Approved 🎉
⇒ Lenmeldy (atidarsagene autotemcel)
⇒ early-onset MLD
⇒ BLA
⇒ PDUFA: 3/18/24
$Esperion Therapeutics(ESPR.US$ : Approved 🎉
⇒ Nexletol (bempedoic acid) & Nexlizet (bempedoic acid and ezetimibe)
⇒ CV risk reduction, primary hyperlipidemia (HeFH)
⇒ sNDA
⇒ PDUFA: 3/31/24
📌 This week’s PDUFAs:
$Merck & Co(MRK.US$ : 🤔
⇒ Sotatercept
⇒ Pulmonary arterial hypertension
⇒ BLA
⇒ PDUFA: 3/26/24...
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$AbbVie(ABBV.US$ to acquire $Landos Biopharma(LABP.US$
⇒ $137.5M deal at $20.42/sh 💰💰
⇒ strengthens portfolio in inflammatory & autoimmune diseases
⇒ Adds lead asset NX-13 (Ph2 trial UC)
$Nuvation Bio(NUVB.US$ to acquire AnHeart Therapeutics
⇒ all-stock transaction
⇒ transforms NUVB into late-stage global oncology company
⇒ Includes taletrectinib with ongoing trials NSCLC)
$Novo-Nordisk A/S(NVO.US$ to acquire Cardior Pharmaceuticals
⇒ 1.025 B euros deal 💰💰
⇒ strengthens pi...
⇒ $137.5M deal at $20.42/sh 💰💰
⇒ strengthens portfolio in inflammatory & autoimmune diseases
⇒ Adds lead asset NX-13 (Ph2 trial UC)
$Nuvation Bio(NUVB.US$ to acquire AnHeart Therapeutics
⇒ all-stock transaction
⇒ transforms NUVB into late-stage global oncology company
⇒ Includes taletrectinib with ongoing trials NSCLC)
$Novo-Nordisk A/S(NVO.US$ to acquire Cardior Pharmaceuticals
⇒ 1.025 B euros deal 💰💰
⇒ strengthens pi...
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The iPhone made Apple $Apple(AAPL.US$ the biggest company in the world. Will Nvidia's $NVIDIA(NVDA.US$ chips make the chip leader the biggest company in the globe in the future? Well it could happen. It's not certain. So here are three certainties and some 'cheaper' ways to get partake in Nvidia's growth
Firstly note that 24 investment banks and analysts reiterated Nvidia as a buy this week. Most think Nvidia's shares will ...
Firstly note that 24 investment banks and analysts reiterated Nvidia as a buy this week. Most think Nvidia's shares will ...
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$Eledon Pharmaceuticals(ELDN.US$ 10%🟢
First-ever Transplant of Genetically Modified Kidney
⇒ Pig to a Human
⇒ Use of Tegoprubart (anti-CD40L antibody)
⇒ Immunosuppressive treatment
$Bristol-Myers Squibb(BMY.US$
⇒ First CAR T Cell Therapy approval in the EU
⇒ Abecma
First-ever Transplant of Genetically Modified Kidney
⇒ Pig to a Human
⇒ Use of Tegoprubart (anti-CD40L antibody)
⇒ Immunosuppressive treatment
$Bristol-Myers Squibb(BMY.US$
⇒ First CAR T Cell Therapy approval in the EU
⇒ Abecma
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