Today's Pre-Market Stock Movers: FCNCA, NVS, ROKU, CAT and More

$Novartis AG(NVS.US)$ +6.21% (The Swiss pharmaceutical company reported positive top-line results from a trial of breast-cancer drug Kisqali. Novartis said Kisqali plus endocrine therapy "significantly reduced the risk of disease recurrence" compared with standard endocrine therapy alone.)

$Iovance Biotherapeutics(IOVA.US)$ +8.68% (The cancer-therapy developer, gained 10.3% in premarket trading after saying Friday it completed a rolling biologics license application submission to the Food and Drug Administration for lifileucel, a melanoma therapy.)

$Roku Inc(ROKU.US)$ +3.67% (The streaming device company was upgraded to Positive from Neutral at Susquehanna.)

$Carnival(CCL.US)$ +1.84% (The cruise ship operator, is scheduled to report quarterly earnings before the stock market opens Monday.)

$Caterpillar(CAT.US)$ -1.20% (Shares of the maker of construction and mining equipment were downgraded to Underperform from Neutral at Baird, the Fly reported.)

$BioNTech(BNTX.US)$ -3.42% (The German biotechnology company, was falling in premarket trading after saying it expects revenue to fall more than expected this year as demand wanes for Covid vaccines.)