Today's Pre-Market Stock Movers: AAL, ZS, DICE, Crude and More

• $New Relic(NEWR.US)$ +3.8% (guidance), $American Airlines(AAL.US)$ +2% (guidance)

• $DICE THERAPEUTICS, INC.(DICE.US)$ +66.5% (announces "positive" topline data from its Phase 1 clinical trial of DC-806 an oral small molecule antagonist of the pro-inflammatory cytokine IL-17)

• $Albireo Pharma(ALBO.US)$ +17.2% (reports positive topline data from Phase 3 Trial of Bylvay (odevixibat) in Alagille Syndrome)

• $SeaSpine(SPNE.US)$ +16.7% (Orthofix and SeaSpine (SPNE) to combine in merger of equals to create leading global spine and orthopedics company; issue guidance)

• $Joby Aviation(JOBY.US)$ +10.4% (Joby Aviation and Delta (DAL) partner to pioneer home-to-airport transportation)

• $Tejon Ranch(TRC.US)$ +4.8% (appoints Drew Hammer as CFO)

• $Angi Inc(ANGI.US)$ +4.4% (CEO steps down; appoints new CEO)

• $Brookdale Senior Living(BKD.US)$ +1.5% (reports September 2022 occupancy)

• $Leggett & Platt(LEG.US)$ -7.7% (lowers FY22 outlook), $AZZ Inc(AZZ.US)$ -6.9%, $ASE Technology(ASX.US)$ -4.1% (Sep revs)

• $Orthofix Medical(OFIX.US)$ -11.7% (Orthofix and SeaSpine (SPNE) to combine in merger of equals to create leading global spine and orthopedics company; issue guidance)

• $Rigel Pharmaceuticals(RIGL.US)$ -8.8% (not expected to file sNDA; reducing workforce)

• $Zscaler(ZS.US)$ -3.6% (President resigning)

• $Sonoco Products(SON.US)$ -3% (subsidiary expands packaging program in Europe)

• $United States Oil Fund LP(USO.US)$ -1.7% (crude oil futures trading lower)

• $Cohen & Steers(CNS.US)$ -1.2% (reports preliminary AUM)